We report a case of liver damage in an elderly patient after the use of herbal products of Hypericum perforatum and copaiba (Copaifera langsdorffii Desf). Hepatotoxicity related to Hypericum perforatum is anecdotally known, but for copaiba, widely used as anti-inflammatory, there is just experimental data in the national literature. This report aimed to draw attention to the possible toxic effe...

zinc and iron nano-oxides (100 ppb) were promoted the hypericin and hyperforin production in hypericum perforatum cell suspension culture. high performance liquid chromatography method was used for detectection and identification of hypericin and hyperforin in h. perfuratum cell suspension cultures elicited with different concentrations of zinc and iron nano-oxide (0, 50, 100 and 150 ppb) after...

In this study, plant oils of Hypericum perforatum, Sesamum indicum, Nigella sative were investigated for their in vitro antibacterial activity against Vibrio anguillarum and Lactococcus garvieae. Antibacterial activity was found to show with oil of Nigella sative. It was determined formed on the diameter of inhibition (inhibition zone: 18 mm) of the oil against Vibrio anguillarum and Lactococcu...

St. John's wort is a widely used medicinal plant. The quality of herbal drug, which is in most of the cases collected from nature, varies. Therefore, the aim of the present study was detailed chemical characterization of Hypericum perforatum subsp. perforatum samples collected in close time intervals during flowering and fruitification with the purpose to state the phenological stage characteri...

Adhyperforin is a novel constituent of Hypericum perforatum L., but its antidepressant-like activity remains unclear. To explore that, several well-validated animal models of depression as well as neurotransmitter reuptake and transporter binding assays were conducted. The results showed adhyperforin could reduce the immobility time of mice in the forced swimming test and tail suspension assay,...

Hyperforin is a pharmacologically active component of the medicinal plant Hypericum perforatum (St. John's wort), recommended as a treatment for a range of ailments including mild to moderate depression. Part of its action has been attributed to TRPC6 channel activation. We found that hyperforin induces TRPC6-independent H(+) currents in HEK-293 cells, cortical microglia, chromaffin cells and l...

Helicobacter pylori is one of the important causes chronic gastritis, peptic ulcer, stomach cancer in humans. The importance these diseases has led to development effective drug treatment regimens against them. basis this study determination effects some medicinal plants on in-vitro growth H. and their antimicrobial antioxidant potential. For purpose, different parts 15 plant species were extra...

1. Hypericum perforatum , St John’s wort, is an invasive weed of natural and agroecosystems in south-eastern Australia. In previous work we used a long-term data set to determine which plant traits and environmental factors influence population growth and persistence in this species. These results were then used to parameterize an individualbased model of the population dynamics of H. perforatu...

Hypericum perforatum (HP), better known as St. John's Wort, has been used clinically for centuries. Modern usage is still quite diverse and includes kidney and lung ailments, insomnia and depression. Standardised extracts of HP are widely used in the treatment of psychovegetative disorders and especially for mild forms of depression. Several bioactive constituents of this plant may play importa...

Amaç: Bitkilerden elde edilen uçucu yağlar, geleneksel sentetik böcek öldürücülere çevre dostu alternatifler sağlayabilir. Bu çalışmada beş farklı esansiyel yağın (Thymus vulgaris, Piper nigrum, Syzygium aromaticum, Hypericum perforatum, Papaver somniferum) Musca domestica larvalarına karşı etkisinin değerlendirilmesi amaçlanmıştır. Yöntem: Her yağ çeşidinin üç dozu (% 1, % 3 ve 6) tekerrürlü o...