نتایج جستجو برای: gynecologic tumors
تعداد نتایج: 183856 فیلتر نتایج به سال:
Immune checkpoint inhibitors have become an area of intense interest in oncology and are actively being studied in a variety of cancer types with a wide range of success. In vitro data suggest mechanisms by which radiation can activate the immune system, and ongoing studies are exploring the potential interaction of checkpoint inhibitors with radiotherapy in both preclinical and clinical settin...
Vulvar cancer is a rare disease both in Spain and in the rest of the world. The incidence ranges from 0.5 to 3 cases per 100,000 women per year. The common symptom of vulvar cancer is a permanent itching. Vulvar surgery research has found that complications such as comorbidity, humidity, dehiscence and infections are among the most frequent reasons for delaying hospital discharges. This is a re...
Leiomyomas are common benign gynecologic tumors occurring in up to 30% of women. Round ligament leiomyomas however are very rare and, if symptomatic, can present as an inguinal hernia. We report the case of a 47-year-old woman who presented with an irreducible inguinal mass consistent with an incarcerated hernia. Intraoperatively, the mass was found to be a round ligament leiomyoma, a diagnosis...
Corresponding author: Magdalena Magnowska MD, PhD Department of Gynecologic Oncology Chair of Gynecology, Obstetrics and Gynecologic Oncology Poznan University of Medical Sciences 33 Polna St 60-535 Poznan, Poland Phone: +48 618 419 330 Fax: +48 616 599 645 E-mail: [email protected] 1Department of Gynecologic Oncology, Chair of Gynecology, Obstetrics and Gynecologic Oncology, Poznan University of Me...
Coexpression of Kit ligand and c-kit has been reported in some gynecologic tumors. To determine whether imatinib mesylate is useful in ovarian epithelial tumors, we performed immunohistochemical and mutational analysis. The cases consisted of 33 cases, which included 13 serous cystadenocarcinomas, 1 borderline serous tumor, 8 mucinous cystadenocarcinomas, 6 borderline mucinous tumors and 5 clea...
Serous endometrial cancer is a clinically aggressive type of uterine cancer, responsible for a disproportionate incidence of advanced stage disease, recurrences and deaths. Serous endometrial cancers are characterized by alteration of p53, STK15, p16, and HER2. The purpose of this review is to describe the current understanding of the role of the HER-2/neu pathway in the carcinogenesis of serou...
Ovarian cancer represents the most lethal gynecologic malignancy, primarily due to a lack of early detection, which results in most patients being diagnosed at an advanced stage of disease. Though the ovarian surface epithelium is thought to provide the primary site of tumorigenesis, the exact etiology of the various tumor types associated with this disease remain undefined. Recent evidence sug...
a Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ohio State University College of Medicine, Columbus, OH, United States b Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Pennsylvania Hospital, Philadelphia, PA, United States c Department of Gynecologic Oncology and Reproductive Medicine, The Univers...
There has been significant progress in the understanding of the pathology and molecular biology of rare ovarian cancers, which has helped both diagnosis and treatment. This paper provides an update on recent advances in the knowledge and treatment of rare ovarian cancers and identifies gaps that need to be addressed by further clinical research. The topics covered include: low-grade serous, muc...
Endometrial stromal sarcomas are rare gynecologic malignancies characterized by the presence of cells that resemble those of the endometrial stroma during the prolipferative phase of the menstrual cycle. They are classified as low grade or high grade tumors depending on the mitotic index, the second one being usually associated with poor prognosis and high recurrence rate. We present the case o...
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