نتایج جستجو برای: gut flora

تعداد نتایج: 69822  

2017
Tomokazu Hata Yasunari Asano Kazufumi Yoshihara Tae Kimura-Todani Noriyuki Miyata Xue-Ting Zhang Shu Takakura Yuji Aiba Yasuhiro Koga Nobuyuki Sudo

Gut lumen serotonin (5-hydroxytryptamine: 5-HT) contributes to several gastrointestinal functions such as peristaltic reflexes. 5-HT is released from enterochromaffin (EC) cells in response to a number of stimuli, including signals from the gut microbiota. However, the specific mechanism by which the gut microbiota regulates 5-HT levels in the gut lumen has not yet been clarified. Our previous ...

2012
Andres Gomez David Luckey Carl J. Yeoman Eric V. Marietta Margret E. Berg Miller Joseph A. Murray Bryan A. White Veena Taneja

BACKGROUND HLA-DRB1 0401 is associated with susceptibility, while HLA-DRB1 0402 is associated with resistance to developing rheumatoid arthritis (RA) and collagen-induced arthritis in humans and transgenic mice respectively. The influence of gut-joint axis has been suggested in RA, though not yet proven. METHODOLOGY/PRINCIPAL FINDINGS We have used HLA transgenic mice carrying arthritis suscep...

2013
Tarini Shankar Ghosh Sourav Sen Gupta Gopinath Balakrish Nair Sharmila S. Mande

The spread of antibiotic resistance, originating from the rampant and unrestrictive use of antibiotics in humans and livestock over the past few decades has emerged as a global health problem. This problem has been further compounded by recent reports implicating the gut microbial communities to act as reservoirs of antibiotic resistance. We have profiled the presence of probable antibiotic res...

Journal: :Journal of immunology 2005
Maria T Abreu Masayuki Fukata Moshe Arditi

The human intestine has evolved in the presence of diverse enteric microflora. TLRs convert the recognition of pathogen-associated molecules in the gut into signals for anti-microbial peptide expression, barrier fortification, and proliferation of epithelial cells. Healing of injured intestinal epithelium and clearance of intramucosal bacteria require the presence of intact TLR signaling. Nucle...

Journal: :Journal of Chemical Ecology 2021

The complex interaction between a higher organism and its resident gut flora is subject of immense interest in the field symbiosis. Many insects harbor community microorganisms their gut. Larvae Spodoptera littoralis, lepidopteran pest, house bacterial that varies both spatially (along length gut) temporally (during insect’s life cycle). To monitor rapid adaptation microbes to conditions gut, G...

Journal: :The EMBO journal 2015
Jens T Van Praet Erin Donovan Inge Vanassche Michael B Drennan Fien Windels Amélie Dendooven Liesbeth Allais Claude A Cuvelier Fons van de Loo Paula S Norris Andrey A Kruglov Sergei A Nedospasov Sylvie Rabot Raul Tito Jeroen Raes Valerie Gaboriau-Routhiau Nadine Cerf-Bensussan Tom Van de Wiele Gérard Eberl Carl F Ware Dirk Elewaut

Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the processes underlying the loss of tolerance against nuclear self-constituents remain largely unresolved. Using mice deficient in lymphotoxin and Hox11, we report that approximately 25% of mice lacking secondary lymphoid organs spontaneously...

2010
Claudia Husseneder Huei-Yang Ho Meredith Blackwell

We investigated the bacterial composition in the gut of Formosan subterranean termites (FST), Coptotermes formosanus Shiraki, collected from southern China (native range) vs. Louisiana, U. S. (introduced range) using 16S rRNA gene sequencing. Overall, we identified 213 bacteria ribotypes from thirteen phyla. The enemy release hypothesis could not be invoked to explain invasion success of FST si...

2012
Ji-Sun Hwang Chang-Rok Im Sin-Hyeog Im

Allergic disorders such as atopic dermatitis and asthma are common hyper-immune disorders in industrialized countries. Along with genetic association, environmental factors and gut microbiota have been suggested as major triggering factors for the development of atopic dermatitis. Numerous studies support the association of hygiene hypothesis in allergic immune disorders that a lack of early ch...

Journal: :Science translational medicine 2014
Viorica Braniste Maha Al-Asmakh Czeslawa Kowal Farhana Anuar Afrouz Abbaspour Miklós Tóth Agata Korecka Nadja Bakocevic Lai Guan Ng Parag Kundu Balázs Gulyás Christer Halldin Kjell Hultenby Harriet Nilsson Hans Hebert Bruce T Volpe Betty Diamond Sven Pettersson

Pivotal to brain development and function is an intact blood-brain barrier (BBB), which acts as a gatekeeper to control the passage and exchange of molecules and nutrients between the circulatory system and the brain parenchyma. The BBB also ensures homeostasis of the central nervous system (CNS). We report that germ-free mice, beginning with intrauterine life, displayed increased BBB permeabil...

2017
Monika Adamczyk-Sowa Aldona Medrek Paulina Madej Wirginia Michlicka Pawel Dobrakowski

Aim. Evaluation of the impact of gut microflora on the pathophysiology of MS. Results. The etiopathogenesis of MS is not fully known. Gut microbiota may be of a great importance in the pathogenesis of MS, since recent findings suggest that substitutions of certain microbial population in the gut can lead to proinflammatory state, which can lead to MS in humans. In contrast, other commensal bact...

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