نتایج جستجو برای: gut bacteria population

تعداد نتایج: 907019  

Journal: :Cell 2015
Virginia A. Pedicord Daniel Mucida

Gut bacteria are known to affect immune cell development, but most intestinal lymphocytes have no direct contact with luminal bacteria. Two studies by Atarashi et al. and Sano et al. shed light on how bacterial adhesion can cue intestinal epithelial cells to direct differentiation of gut T cells.

Journal: :Current Biology 2016
Ray Soto June Round

The majority of bacteria found within the gut are commensals, although it is unclear whether these organisms can elicit systemic immunity. New research indicates that gut-microbiota-specific serum antibodies targeting an epitope conserved among Gram-negative bacteria can protect the host from systemic pathogenic infection.

Journal: :Cell 2014
Henning Seedorf Nicholas W. Griffin Vanessa K. Ridaura Alejandro Reyes Jiye Cheng Federico E. Rey Michelle I. Smith Gabriel M. Simon Rudolf H. Scheffrahn Dagmar Woebken Alfred M. Spormann William Van Treuren Luke K. Ursell Megan Pirrung Adam Robbins-Pianka Brandi L. Cantarel Vincent Lombard Bernard Henrissat Rob Knight Jeffrey I. Gordon

To study how microbes establish themselves in a mammalian gut environment, we colonized germ-free mice with microbial communities from human, zebrafish, and termite guts, human skin and tongue, soil, and estuarine microbial mats. Bacteria from these foreign environments colonized and persisted in the mouse gut; their capacity to metabolize dietary and host carbohydrates and bile acids correlate...

2017
Jiang Hong Li Jay D Evans Wen Feng Li Ya Zhou Zhao Gloria DeGrandi-Hoffman Shao Kang Huang Zhi Guo Li Michele Hamilton Yan Ping Chen

It has become increasingly clear that gut bacteria play vital roles in the development, nutrition, immunity, and overall fitness of their eukaryotic hosts. We conducted the present study to investigate the effects of gut microbiota disruption on the honey bee's immune responses to infection by the microsporidian parasite Nosema ceranae. Newly emerged adult workers were collected and divided int...

2012
Keisuke OZAWA Reiko FUJIWARA Karin WATANABE Kei SONOYAMA

The present study tested the persistence of orally administered bacteria in the gut of suckling mice. We used three bacterial strains: one strain of Lactobacillus johnsonii (designated strain Ms1) that was previously isolated from the mouse stomach, and two strains of L. plantarum, (strain No. 14 and JCM 1149(T)). We detected L. johnsonii Ms1, but neither strain of L. plantarum, in the gut 7 da...

2017
Patrick Smith David Willemsen Miriam Popkes Franziska Metge Edson Gandiwa Martin Reichard Dario Riccardo Valenzano

Gut bacteria occupy the interface between the organism and the external environment, contributing to homeostasis and disease. Yet, the causal role of the gut microbiota during host aging is largely unexplored. Here, using the African turquoise killifish (Nothobranchius furzeri), a naturally short-lived vertebrate, we show that the gut microbiota plays a key role in modulating vertebrate life sp...

2016
Drew D. Kiraly Deena M. Walker Erin S. Calipari Benoit Labonte Orna Issler Catherine J. Pena Efrain A. Ribeiro Scott J. Russo Eric J. Nestler

Addiction to cocaine and other psychostimulants represents a major public health crisis. The development and persistence of addictive behaviors comes from a complex interaction of genes and environment - the precise mechanisms of which remain elusive. In recent years a surge of evidence has suggested that the gut microbiome can have tremendous impact on behavioral via the microbiota-gut-brain a...

2012
Kristina Harris Amira Kassis Geneviève Major Chieh J. Chou

The gut microbiota refers to the trillions of microorganisms residing in the intestine and is integral in multiple physiological processes of the host. Recent research has shown that gut bacteria play a role in metabolic disorders such as obesity, diabetes, and cardiovascular diseases. The mechanisms by which the gut microbiota affects metabolic diseases are by two major routes: (1) the innate ...

Anil Bhandari Anupama Singh, Manjeet Singh Vikas Saharan

      Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine wh...

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