Recently, a successful pose estimation algorithm, called Cascade Pose Regression (CPR), was proposed in the literature. Trained over Pose Index Feature, CPR is a regressor ensemble that is similar to Boosting. In this paper we show how CPR can be represented as a Neural Network. Specifically, we adopt a Graph Transformer Network (GTN) representation and accordingly train CPR with Back Propagati...

BACKGROUND Glyceryl trinitrate (GTN) has been shown to be able to relax the sphincter of Oddi (SO) both in animals and humans. Theoretically, the use of these compounds during and after endoscopic retrograde cholangiopancreatgraphy (ERCP) could relax the biliary and pancreatic sphincters, facilitating cannulation of common bile duct (CBD) during the procedure, or minimizing potential pancreatic...

Introduction: Gestational trophoblastic neoplasia (GTN), is recognized as the most curable gynaecologic malignancy. However, many cases are resistant to first line chemotherapy. Objective: The aim of the study is to report our 5 years experience in the management of GTN cases with special stress on the chemo-resistant cases. Methods: The study was performed through reviewing the records of 51 p...

BACKGROUND Gestational trophoblastic neoplasia (GTN) is a curable disease that involves the development of malignant tumor in the woman after a normal or molar pregnancy. The position of surgery in GTN is not properly specified and is changing due to new chemotherapy protocols. However, the role of surgery is highlighted in chemotherapy-resistant GTN. Other indications of surgery in trophoblast...

INTRODUCTION Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal. This study aimed to assess the efficacy of Glyceryl Trinitrate and Nifedipine in the treatment of chronic anal fissure. METHODS Ninety patients with symptomatic anal fissure in Kathmandu Medical College Teaching Hospital are all...

Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. The overall cure rate in treating these tumors is currently >90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity. Nonmetastatic (stage I) and low-risk metastat...

Background Foot ulceration is caused by a variety of factors including ischemia. GTN is a nitric oxide donor that reliably causes vasodilation, but its potential to improve local vascular supply to at-risk feet has received little attention. When used to supplement standard evidence-based wound care, transdermal GTN produced rapid ulcer healing in four cases of non diabetic and diabetic ulcers....

This study investigates the effect of material parameters of the Gurson-Tvergaard-Needleman (GTN) model on the failure prediction of cellular structures. The effect of elastic modulus, calibration parameter of GTN model, isotropic hardening, fracture strain, and strut diameter on the load-displacement curve of a lattice structure fabricated by Selective Laser Melting (SLM) has been studied by u...

OBJECTIVES In patients with systemic sclerosis (SSc), fingertip digital ulcers (DUs) are believed to be ischaemic, and extensor surface DUs a result of mechanical factors/microtrauma. Our aim was to assess blood flow response to topical glyceryl trinitrate (GTN) compared to placebo in SSc DUs, looking for differences in pathophysiology between fingertip and extensor lesions. METHOD This was a...

Gestational trophoblastic disease describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial), placental site trophoblastic tumour, choriocarcinoma and gestational trophoblastic neoplasia (GTN). Invasive moles are responsible for most cases of localized GTN. Two cases of GTN previously reported in the literature exhibit...