UNLABELLED The Genomic Threading Database currently contains structural annotations for the genomes of over 100 recently sequenced organisms. Annotations are carried out by using our modified GenTHREADER software and through implementing grid technology. AVAILABILITY http://bioinf.cs.ucl.ac.uk/GTD

Vari.ous methods available for the exploitation of atom-probe concentrat ion prof iles are discussed. T h e determinat ion of microstructure Parameters of a nickel base superalloy containing small precipitates is given a s an example.

Specific recognition of the cargo that molecular motors transport or tether to cytoskeleton tracks allows them to perform precise cellular functions at particular times and positions in cells. However, very little is known about how evolution has favored conservation of functions for some isoforms, while also allowing for the generation of new recognition sites and specialized cellular function...

Clostridium difficile is the most common cause of antibiotic-associated nosocomial infection in the United States. C. difficile secretes two homologous toxins, TcdA and TcdB, which are responsible for the symptoms of C. difficile associated disease. The mechanism of toxin action includes an autoprocessing event where a cysteine protease domain (CPD) releases a glucosyltransferase domain (GTD) i...

It is universally recognized that an accurate and precise staging and classification system for gestational trophoblastic neoplasia (GTN) is essential to enable clinicians to assess the prognosis or the risk of patients, to individualize and to optimize their treatment. There have been a variety of staging and classification systems developed by different centres and some are still being used. ...

We evaluated the effect of GnRH on the serum hCG level in gestational trophoblastic disease (GTD). Five patients with GTD were studied. Three patients had hydatidiform mole (two complete and one partial mole) and two had choriocarcinoma. Blood samples were collected immediately before and 30, 60 min after the 100 μg GnRH iv injection, followed by hCG assay. Only one case of choriocarcinoma demo...

The causes of liquation cracking in the heat-affected zone (HAZ) of a cast Mar-M004 superalloy weld were investigated. X-ray diffraction (XRD), electron probe microanalyzer (EPMA), and electron backscatter diffraction (EBSD) were applied to identify the final microconstituents at the solidification boundaries of the cast alloy. Fine borides and lamellar eutectics were present in front of some γ...

background : gestational trophoblastic neoplasia (gtn) refers to malignant lesions that arise from abnormal proliferation of placental trophoblast. even in its metastatic forms gtn is curable with a cure rate of 90-100 %. currently, methotrexate with or without folic acid, andactinomycin d is recommended for low risk gtn. the aim of this study is to compare the efficacy of methotrexate and acti...

We compared field measurements of the biological O 2 saturation anomalies, ΔO /Ar and /N , from simultaneous oceanographic deployments a membrane inlet mass spectrometer optode/gas tension device (GTD). Data Subarctic Northeast Pacific Canadian Arctic Ocean were used to evaluate as an alternative for estimates mixed layer net community production (NCP). observed strong spatial coherence between...