Recent insights into the genetic basis of neurological disease have led to the hypothesis that molecular pathways involved in synaptic growth, development, and stability are perturbed in a variety of mental disorders. Formation of a functional synapse is a complex process requiring stabilization of initial synaptic contacts by adhesive protein interactions, organization of presynaptic and posts...

Short stature is one of the major components of many dysmorphic syndromes. Growth failure may be due to a wide variety of mechanisms, either related to the growth hormone (GH)/insulin-like growth factor axis or to underlying unknown pathologies. In this review, the relatively more frequently seen syndromes with short stature (Noonan syndrome, Prader-Willi syndrome, Silver-Russell syndrome and A...

Endocrine disorders after hematopoietic stem cell transplantation result from the interaction between underlying disease, host characteristics and treatment, including exposure to pre- peri-transplant agents (chemotherapy radiotherapy). In addition, post-transplantation factors, graft-versus-host its especially glucocorticoids, also contribute hormone deficiencies or endocrine disorders. Endocr...

supervisors have critical role in the provision of support in workplace. the present study examined degree of perceived supervisor support related to experienced physical symptoms and psychological distress among employees of isfahan steel company, isfahan, iran. the sample included of 189 employees of the company in 2011 who completed questionnaires about supervisor support, physical symptoms ...

conclusions: these findings demonstrated that cognitive failure and alexithymia had important roles in strengthening and appearance of high-risk behaviors in students with learning disabilities. therefore, considering those problems, precautionary actions might be necessary. results: the results showed that high-risk behaviors had significant positive correlations with difficulty identifying fe...

background substance use in patients with psychiatric disorder is an every-day seen. detection of this comorbidity can significantly affect the treatment of these disorders, as well as substance use. objectives this study has been conducted to determine the prevalence and pattern of substance use in hospitalized psychiatric patients. patients and methods in this cross-sectional study, 210 hospi...