نتایج جستجو برای: grove binding mode

تعداد نتایج: 634239  

Journal: :jundishapur journal of microbiology 0
mehraban falahati department of mycology, iran university of medical sciences, tehran, ir iran sanam nami department of mycology, tehran university of medical sciences, tehran, ir iran; tavanir ave., baharak st., no. 1, tabriz, ir iran. tel: +98-9143114660 farideh zeini department of mycology, health school, tehran university of medical sciences, tehran, ir iran mohsen ghelman department of immunology, iran university of medical sciences, tehran, ir iran zeinab ghasemi department of mycology, health school, tehran university of medical sciences, tehran, ir iran shima nozari department of mycology, health school, tehran university of medical sciences, tehran, ir iran

background dermatophytosis is a cutaneous fungal infection with a worldwide occurrence. in dermatophyte infections, the release of keratinocyte cytokines, in the presence of dermatophyte antigens, causes an acute phase response; subsequently, the acute-phase proteins are produced by hepatocytes. mannose–binding lectin (mbl), an acute-phase protein, also acts as a kind of pattern recognition rec...

Journal: :Neuron 2014
Jens Niewoehner Bernd Bohrmann Ludovic Collin Eduard Urich Hadassah Sade Peter Maier Petra Rueger Jan Olaf Stracke Wilma Lau Alain C. Tissot Hansruedi Loetscher Anirvan Ghosh Per-Ola Freskgård

Although biotherapeutics have vast potential for treating brain disorders, their use has been limited due to low exposure across the blood-brain barrier (BBB). We report that by manipulating the binding mode of an antibody fragment to the transferrin receptor (TfR), we have developed a Brain Shuttle module, which can be engineered into a standard therapeutic antibody for successful BBB transcyt...

Journal: :Protein Engineering, Design and Selection 1999

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