A novel multi-stage noise-shaping (MASH) delta-sigma (∆Σ) Time-to-Digital Converter (TDC) structure is proposed for applications in continuous-time pulsed time-offlight (TOF) rangefinders for nuclear reactor remote sensing, which requires both high resolution and multi MGy gamma-dose radiation tolerance. The converter, implemented in 0.13 μm CMOS, achieves a time resolution of 5.6 ps and an ENO...

We describe an field-programmable gate arrays based (FPGA), 96-channel, Time-to-Digital converter (TDC) and trigger logic board intended for use with the Central Outer Tracker (COT) [T. Affolder et al., Nucl. Instr. and Meth. A 526 (2004) 249] in the CDF Experiment [The CDF-II detector is described in the CDF Technical Design Report (TDR), FERMILAB-Pub-96/390-E. The TDC described here is intend...

BACKGROUND The optimal therapy for preventing recurrent stroke in people with cryptogenic stroke and patent foramen ovale (PFO) has not been defined. The choice between medical therapy (antithrombotic treatment with antiplatelet agents or anticoagulants) and transcatheter device closure has been the subject of intense debate over the past several years. Despite the lack of scientific evidence, ...

BACKGROUND Dialysate-based, on-line measurements of Kt/V and protein catabolic rate (PCR) in dialysis patients have been considered more accurate compared with measurements on the blood side during dialysis. The primary aim of this study was to compare total removed urea (TRU) and PCR, normalized to body weight (nPCRw), obtained by three dialysate-based methods: (i) on-line ultraviolet (UV) abs...

A new learning scheme called time divergence-convergence – TDC – is proposed for two-layer dynamic synapse neural networks – DSNN. DSNN is an artificial neural network model, in which the synaptic transmission is modeled by a dynamic process and the information between neurons are transmitted through spike timing. In TDC, the intra-layer neurons of a DSNN are trained to map input spike trains t...

OBJECTIVE A less invasive method to assess internal thoracic artery (ITA) graft function after coronary artery bypass grafting (CABG) is desired. This study reports the novel method to estimate ITA graft function using CT angiography. MATERIALS AND METHODS Fifty ITA grafts were assessed. Hounsfield Unit transition of each graft on the same cross section was detected during the Test Bolus Inje...

We describe the construction and characterization of a genomically recoded organism (GRO). We replaced all known UAG stop codons in Escherichia coli MG1655 with synonymous UAA codons, which permitted the deletion of release factor 1 and reassignment of UAG translation function. This GRO exhibited improved properties for incorporation of nonstandard amino acids that expand the chemical diversity...

Responses of Cola nitida and acuminata to NPK Super-gro fertilizers on seedling development, field establishment, canopy characteristics were investigated in 2019-2020. Seedlings the two species transplanted as a randomized complete block design with three replications field. Fertilizer treatments imposed shoot root growth parameters cola monitored for growing seasons. From results, application...

Transcriptional cofactors are essential for proper embryonic development. One such cofactor in Drosophila, Degringolade (Dgrn), encodes a RING finger/E3 ubiquitin ligase. Dgrn and its mammalian ortholog RNF4 are SUMO-targeted ubiquitin ligases (STUbLs). STUbLs bind to SUMOylated proteins via their SUMO interaction motif (SIM) domains and facilitate substrate ubiquitylation. In this study, we sh...

We present a Chandra/ACIS-I observation of GRO J1744–28. We detected a source at a position of R.A = 17 44 33.09 and Dec. = –28 44 27.0 (J2000.0; with a 1σ error of ∼0.8 arcseconds), consistent with both ROSAT and interplanetary network localizations of GRO J1744–28 when it was in outburst. This makes it likely that we have detected the quiescent X-ray counterpart of GRO J1744– 28. Our Chandra ...