we present a 24-year-old female referred with non-healing wound of a few days duration on anterior aspect of her right foreleg. biopsy of the wound was reported to be pyoderma gangrenosum on pathologic report. further work up of the patient for high grade fever and occasional leukopenias revealed the diagnosis of cyclic neutropenia. treatment with granulocyte colony-stimulating factor (g-csf) r...

Abbreviations: acute myeloid leukemia, (AML); American Society of Clinical Oncology, (ASCO); bone marrow, (BM); end stage renal disease, (ESRD); erythropoietin, (EPO); granulocyte colony-stimulating factor, (G-CSF); Granulocyte-macrophage colony-stimulating factor, (GM-CSF); hematopoietic growth factors, (HGFs); hematopoietic stem cell, (HSC); hemoglobin, (Hgb); idiopathic thrombocytopenic purp...

2005;112:214-223. 15. Laflamme MA, Gold J, Xu C, et al. Formation of human myocardium in the rat heart from human embryonic stem cells. Am J Pathol. 2005;167:663671. 16. Murry CE, Soonpaa MH, Reinecke H, et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature. 2004;428: 664-668. 17. Murry CE, Field LJ, Menasché P. Cell-based cardiac repair...

Sweet syndrome was first described in 1964, at which time it was termed acute febrile neutrophilic dermatosis.1 Up to 20% of patients with Sweet syndrome have an associated malignancy, of whom about 85% have a hematologic disorder.2 The hallmark of Sweet syndrome is a nodular and diffuse dermal infiltrate of neutrophils identified on biopsy.3 The mechanism of the syndrome is not completely unde...

Pulmonary alveolar proteinosis (PAP) is a rare disease characterised by the accumulation of protein-rich liquid in the alveoli. Even though its pathogenesis is unknown, it is suggested that the accumulation of phospholipids-rich proteinaceous material, positively painted with periodic acid-Schiff (PAS), in the alveoli results from degeneration of the maturation or functions of alveolar macropha...