Membrane deterioration in plant senescence is commonly associated with progressive decreases in membrane phospholipid content. This study investigated the expression and regulation of phospholipase D (PLD; EC 3.1.4.4) during senescence in castor bean (Ricinus communis L. cv Hale) leaf discs. The rate of leaf senescence was accelerated by 50 [mu]M abscisic acid and was attenuated by 50 [mu]M cyt...

The 53-year-old female patient had suffered massive subarachnoid bleeding due to rupture of left-localized aneurysm of the anterior communicant artery. Following the neurosurgical intervention, deterioration of consciousness related to strong vasospasm occurred. Cerebral CT examination was performed, showing a 0.5 cm ischaemic lesion of the left hippocampal fornix. Due to intensive therapy, the...

Osteoporosis is a major public health burden that is expected to further increase as the global population ages. In the last twenty years, advanced glycation end products (AGEs) have been shown to be critical mediators both in the pathogenesis and development of osteoporosis and other chronic degenerative diseases related to aging. The accumulation of AGEs within the bone induces the formation ...

CARDIOVASCULAR aging is a complex phenomenon associated with a gradual, yet progressive, deterioration in cardiovascular function.1-3 The etiology of this deterioration in function is poorly understood, but atherosclerosis and, in particular, coronary artery disease seem to be a factor. Cardiovascular aging and atherosclerosis appear to be universal phenomena, but their rate of development and ...

In this paper, we introduce a new fuzzy metric based on gradual numbers. Firstly, the concept of gradual metric spaces is introduced. And then, basic topological concepts in gradual metric spaces are presented and their properties are investigated. Mathematics Subject Classification: 54E35, 03E72

Mining emerging patterns aims at contrasting data sets and identifying itemsets that characterise a data set by contrast to a reference data set, so as to capture and highlight their differences. This paper considers the case of emerging gradual patterns, to extract discriminant attribute co-variations. It discusses the specific features of these gradual patterns and proposes to transpose an ef...

We present gradual liquid type inference, a novel combination of refinement types with gradual refinements that range over a finite set of SMT-decidable predicates. This finiteness restriction allows for an algorithmic inference procedure where all possibly valid interpretations of a gradual refinement are exhaustively checked. Thanks to exhaustive searching we can detect the safe concretizatio...

Several cross-sectional studies and one longitudinal study were conducted on the language abilities of various cohorts of persons with Down syndrome aged between 14 and 50 years. No significant difference was observed on any of the receptive and productive morphosyntactic and lexical measures used, suggesting no marked change in the language of these persons from adolescence onto late adulthood...

OBJECTIVE To report the case of an adult patient who developed auditory complaints following xylene exposure, and to review the literature on the effects of solvent exposure on hearing. CASE REPORT The patient presented with a gradual deterioration in his ability to hear in difficult acoustic environments and also to hear complex sounds such as music, over a 40-year period. His symptoms began...

We report the case of an 18-year-old woman who was referred to our outpatient clinic because of a 2-week history of sore throat, high fever, and neck tenderness unresponsive to a 7-day amoxicillin/clavulanic acid course. Infectious mononucleosis was initially suspected, but an extremely high value of procalcitonin and clinical deterioration suggested a bacterial sepsis, prompting the patient ad...