T2*-weighted multi-echo gradient-echo magnetic resonance imaging and its reciprocal R2* are used in brain imaging due to their sensitivity to iron content. In patients with multiple sclerosis who display pathological alterations in iron and myelin contents, the use of R2* may offer a unique way to untangle mechanisms of disease. Coronal slices from 8 brains of deceased multiple sclerosis patien...

Abstract Unmonitored cardiac images of a rat were acquired using standard gradient echo sequences to study the artefact ghosting mainly caused by heart and respiration motion. All imaging experiments performed transceiver circular-shaped coil preclinical magnetic resonance imager at 7 T. Heart showed along frequency encoding direction. However image quality was not drastically affected this typ...

One of several techniques that achieve contrast by preparing the magnetization in some way and then sampling the prepared magnetization via a conventional imaging sequence, magnetization transfer offers advantages that have proven valuable in the study of white matter disorders. In the most common implementation, the magnetization transfer preparation is integrated into a gradient echo pulse se...

OBJECTIVES To evaluate the accuracy of magnetic resonance imaging measurements of cartilage tissue-mimicking phantoms and to determine a combination of magnetic resonance imaging parameters to optimize accuracy while minimizing scan time. METHOD Edge dimensions from 4 rectangular agar phantoms ranging from 10.5 to 14.5 mm in length and 1.25 to 5.5 mm in width were independently measured by tw...

BACKGROUND AND PURPOSE At 7T MR imaging, T2*-weighted gradient echo has been shown to provide high-resolution anatomic images of gray matter lesions. However, few studies have verified T2*WI lesions histopathologically or compared them with more standard techniques at ultra-high-field strength. This study aimed to determine the sensitivity of T2WI and T2*WI sequences for detecting cortical GM l...

BACKGROUND AND PURPOSE 2D gradient-echo imaging is sensitive to T2* lesions (hemorrhages, mineralization, and vascular lesions), and susceptibility-weighted imaging is even more sensitive, but at the cost of additional scan time (SWI: 5-10 minutes; 2D gradient-echo: 2 minutes). The long acquisition time of SWI may pose challenges in motion-prone patients. We hypothesized that 2D SWI/phase unwra...

INTRODUCTION – Images obtained with gradient-echo echo planar imaging (GRE-EPI) suffer from magnetic field variations within the brain, such as in regions adjacent to air-tissue interfaces. In these regions, magnetic field inhomogeneities cause spins to dephase more rapidly, resulting in signal dropouts. Thus, conventional GRE-EPI pulse sequences used for dynamic susceptibility-contrast perfusi...