BACKGROUND In HIV infection, dynamic marginal structural models have estimated the optimal CD4 for treatment initiation to minimize AIDS/death. The impact of CD4 observation frequency and grace periods (permitted delay to initiation) on the optimal regimen has not been investigated nor has the performance of dynamic marginal structural models in moderately sized data sets-two issues that are re...

BACKGROUND The GRACE Score was derived and validated from a cohort in which octogenarians and nonagenarians were poorly represented. OBJECTIVE To test the accuracy of the GRACE score in predicting in-hospital mortality of very elderly individuals with acute coronary syndromes (ACS). METHODS Prospective observational study conducted in the intensive coronary care unit of a tertiary center fr...

OBJECTIVES The Global Registry of Acute Coronary Events (GRACE) registry reported that the in-hospital risk of death from non-ST elevation myocardial infarction (NSTEMI) is 5%, with an 11% mortality by 6 months. Prospective Registry of Acute Ischaemic Syndromes in the UK demonstrated that the overall risk of death from NSTEMI over 4 years is 25%. In GRACE, while 28% of patients received percuta...

BACKGROUND Although cardiovascular disease is the major cause of premature death among Indigenous peoples in several advanced economies, no acute coronary syndrome (ACS) risk models have been validated in Indigenous populations. We tested the validity and calibration of three Global Registry of Acute Coronary Events (GRACE) scores among Aboriginal and non-Aboriginal Australians. METHODS GRACE...

BACKGROUND Although the TIMI score is the one most frequently used in acute coronary syndromes (ACS) without ST-segment elevation, the GRACE score has potential prognostic superiority, as it was created based on an observational registry, part of the variables is treated in a semi-quantitative form and renal function is taken into account in its calculation. OBJECTIVE To test the hypothesis t...

AIM To compare the prognostic performance of three major risk scoring systems including global registry for acute coronary events (GRACE), thrombolysis in myocardial infarction (TIMI), and prediction of 30-day major adverse cardiovascular events after primary percutaneous coronary intervention (RISK-PCI). METHODS This single-center retrospective study involved 200 patients with acute coronary...

Water storage change has implications not only for the hydrological cycle, but also for sustainable water resource management in especially semi-arid river basins. Satellite/remote sensing techniques have gained increasing application in monitoring basin and regional hydrological processes in recent decades. In this study, the latest version of GRACE (Gravity Recovery and Climate Experiment) is...

The satellite mission GRACE (Gravity Recovery and Climate Experiment) provides monthly solutions of the global gravity field of the Earth. Temporal variations in gravity reflect mass redistributions over the Earth. Those mass movements are caused by physical phenomena such as ice sheet dynamics, accumulation of hydrological masses over land, the dynamics in the solid Earth and the dynamics in t...

BACKGROUND The Thrombolysis in Myocardial Infarction (TIMI) risk scores for Unstable Angina/Non-ST-elevation myocardial infarction (UA/NSTEMI) and ST-elevation myocardial infarction (STEMI) and the Global Registry of Acute Coronary Events (GRACE) risk scores for in-hospital and 6-month mortality are established tools for assessing risk in Acute Coronary Syndrome (ACS) patients. The objective of...