We use a glass box approach based on decision trees to understand glycoprotein binding with biomedical polymers.

introduction: in order to determine the multidrug resistance (mdr) phenotype due to p-glycoprotein expression in haematological malignancies including acute myeloblastic leukemia (aml), a well-characterized p-gp expressing cell line was required to validate and standardize flow cytometric assays and to calibrate instruments. therefore, this resistant subline of k562 was established for the firs...

glanzmann’s thrombasthenia (gt) is an autosomal recessive inherited platelet function defect characterized by normal platelet count, prolonged bleeding time and abnormal clot retraction. this disease typically presents in infancy or early childhood and has proven to have very good prognosis. in this case study, a 22‑year‑old gt patient who also developed human immunodeficiency virus (hiv) infec...