UNLABELLED Ginseng is widely used for its promising healing and restorative properties as well as for its possible tonic effect in traditional medicine. Nowadays, many studies focus on purified individual ginsenoside, an important constituent in ginseng, and study its specific mechanism of action instead of whole-plant extracts on cardiovascular diseases (CVDs). Of the various ginsenosides, pur...

bidity and mortality throughout the world, has been associated with a variety of biomedical and psychological factors. In Western populations, CAD and myocardial ischemia are the most common causes of heart failure, which occurs when the heart fails to pump blood at a rate needed to meet metabolic requirements under normal cardiac filling pressure. Patients who survive myocardial infarction res...

Ginsenosides separated by silica gel TLC blotted to a polyvinylidene difluoride (PVDF) membrane was treated with a NaIO4 solution followed by bovine serum albumin (BSA), resulting in a ginsenoside-BSA conjugate on a PVDF membrane. The blotted bands were stained with anti-ginsenoside Rg1 and Rb1 monoclonal antibodies (MAbs). The newly established double staining with the Western blotting methods...

This application note describes a fast UHPLC method for the determination of 20 ginsenosides. The developed method allows for the determination of 20 ginsenosides in less than 35 minutes. A binary high pressure gradient is used at a flow rate of 0.6 ml/min. By applying a Bluespher 100-2 C18 column in the dimension 150 x 2 mm ID, the total run time could be reduced to less than 41 minutes when a...

Ginsenosides, the bioactive components of ginseng, can be divided into two major groups, namely 20(S)-protopanaxatriol (e.g. Re, Rg1, Rg2, and Rb3) and 20(S)-protopanaxadiol (e.g. Rb1, Rb2, Rc, and Rd). Biological and environmental factors may affect the content of ginsenosides in different parts of ginseng plant. Evidence from pharmacokinetic and metabolic studies of Re demonstrated that (1) t...

Wound healing is the process of skin and soft tissue repair following an injury. Angiogenesis essential in wound plays important role regeneration. Ginseng mainly composed saponins protopanaxadiol-based ginsenosides, namely Rb1, Rb2, Rc, Re, Rg1, Rf. 20(S)-protopanaxadiol (PPD) 20(S)-protopanaxatriol (PPT) are aglycones ginsenosides produced by metabolic processes heat treatment. This study aim...

Abstract Ginsenosides are the most valuable and pharmacologically active triterpenoid saponins found in Panax ginseng . Although light quality affects ginsenoside content, little is known about underlying genetic regulatory mechanisms. Additionally, correlation between adaptability of to shade biosynthesis remains poorly understood. In present study, transcriptome analysis seedlings using RNA s...

Abstract Kombucha is a healthy carbonated beverage made by fermenting tea extracts such as green and black through symbiotic culture of bacteria yeast. In this study, fermentation characteristics radical scavenging activity ginseng berry kombucha (GBK) Saccharomyces cerevisiae M-5 Gluconobacter oxydans were measured. As time increased, pH decreased titratable acidity increased. Reducing sugars ...

Araliaceae) is frequently used as a traditional medicine, taken orally, in China, Korea, Japan and other Asian countries. The major components of ginseng, the ginsenosides, are glycosides that contain an aglycone with a dammarane skeleton. These ginsenosides have been reported to show various biological activities, including immunomodulatory effect, anti-inflammatory activity and antitumor effe...