Background: Gestational trophoblastic diseases (GTD) are important and interesting part of gynecological oncology. Women diagnosed with GTD should be counseled that about 8% become malignant GTN is a significant cause morbidity, fertility loss unfortunately mortality in young women. All form produce B- hCG monitoring this hormone precise biomarker for screening, diagnosis, therapeutic response ...

BACKGROUND: Placental site trophoblastic tumor (PSTT) is a rare and unique form of gestational trophoblastic disease (GTD). This tumor represents a neoplastic transformation of intermediate trophoblastic cells. We document a case of long term remission in a patient with metastatic PSTT. CASE PRESENTAION: A 27-year-old patient with metastatic PSTT was treated with combination therapy (chemothera...

Gestational trophoblastic disease (GTD) is a condition that develops from abnormal proliferation of placental trophoblasts. A rare division GTD partial mole with co-existing live fetus-a also referred to as “sad fetus syndrome” We report case 24-year-old, primigravida 26 weeks gestational age single intrauterine gestation coexisting molar pregnancy who had spontaneous preterm delivery at 27 wee...

Choriocarcinoma is an aggressive malignant disease that originates in the trophoblastic cells of the placenta, characterized by early hematogenous spread to the lungs. It belongs to the far spectrum of gestational trophoblastic disease (GTD), a subset of germ cell tumor. It is a hypervascular tumor composed of sheets of malignant cytotrophoblast and syncytiotrophoblast metastasizing hematogenou...

BACKGROUND Gestational trophoblastic neoplasia (GTN) is a malignant disease which occurs in women of reproductive age. Treatment of GTN has an excellent outcome and further pregnancies can be expected. However, data concerning quality of life in these cancer survivor patients are limited. This study aimed to assess quality of life in women who were diagnosed with GTN and remission after treatme...