نتایج جستجو برای: geraniol
تعداد نتایج: 639 فیلتر نتایج به سال:
Camptothecin (CPT) belongs to a group of monoterpenoidindole alkaloids (TIAs) and its derivatives such as irinothecan and topothecan have been widely used worldwide for the treatment of cancer, giving rise to rapidly increasing market demands. Genes from Catharanthus roseus encoding strictosidine synthase (STR) and geraniol 10-hydroxylase (G10H), were separately and simultaneously introduced in...
Trypanocidal Activity of Oil of the Young Leaves of Nepeta cataria L. Obtained by Solvent Extraction
Trypanocidal activity was found in the volatile oil of the Young leaves of Nepeta cataria L. which has been extracted by diethyl ether and analyzed by GC and GC/MS. Four compounds in the oil of N. cataria, representing 97.53% of the oil were identified. The oil was enriched of monoterpenes with α- citral (51.95%) as the major compound. Other main compounds were β- citronellol (9.03%), geraniol ...
Mevalonate Kinase Deficiency (MKD) is a rare autosomal recessive inborn disorder of cholesterol biosynthesis caused by mutations in the mevalonate kinase (MK) gene, leading to MK enzyme decreased activity. The consequent shortage of mevalonate-derived isoprenoid compounds results in an inflammatory phenotype, caused by the activation of the NALP3 inflammasome that determines an increased caspas...
Backgroud:Lippia alba (Verbenaceae) is a plant widely used in folk medicine to treat various diseases. The present work deals with the chemical composition of the crude essential oil extracted from leaves of L. alba and evaluation of its antimicrobial and cytotoxic activities. Methods: Leaves of L. alba were extracted by hydrodistillation and analyzed by gas chromatography/mass spectrometry (GC...
The isolation and characterization of the lignan meso-dihydroguaiaretic acid (MDGA) from Larrea tridentata and its activity against Mycobacterial tuberculosis has been demonstrated, but no information regarding its mechanism of action has been documented. Therefore, in this study we carry out the gene expression from total RNA obtained from M. tuberculosis H37Rv treated with MDGA using microarr...
MOTIVATION With the advent of meta-'omics' data, the use of metabolic networks for the functional analysis of microbial communities became possible. However, while network-based methods are widely developed for single organisms, their application to bacterial communities is currently limited. RESULTS Herein, we provide a novel, context-specific reconstruction procedure based on metaproteomic ...
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