conclusions there were significant linkages between hcv genotypes and il28b genotypes/alleles. patients with a favorable il28b and genotypes 1 and 4 hcv infection stand a better chance to clear hcv in the acute phase. objectives this meta-analysis was designed to determine the world-wide distribution patterns of il28b genotypes and alleles, and to find possible linkages between il28b and hcv ge...

Genotype imputation is now an essential tool in the analysis of genome-wide association scans. This technique allows geneticists to accurately evaluate the evidence for association at genetic markers that are not directly genotyped. Genotype imputation is particularly useful for combining results across studies that rely on different genotyping platforms but also increases the power of individu...

This study was conducted to investigate the association between polymorphism of FASN gene with fatty acid content in Awassi sheep. A total 100 male sheep ages one and two a half years old were used this study. Phenotypic measurement recorded at slaughter, from each animal, longissimus dorsi (LD) muscle samples taken analyze profile. Genotyping, sequencing reactions, silico tools performed confi...

background: the effect of il 28 b polymorphism on sustained virology response (svr) in patients with hepatitis c genotype 1 varies among races.â  multiple studies have shown that the svr is two or three times higher in patients with cc genotype compared to those with tt genotype. this study aims to assess the relationship between il 28 b polymorphism and svr in iranian patients. materials and m...

background clinical observations have shown that patients infected with chronic hepatitis b virus (hbv) genotype c versus genotype b had a higher load of the virus, more serious illness, and poorer responses to antiviral therapy and prognosis. however, the disparity between the two has not been clarified. objectives to explore possible relationship between hbv genotypes b and c and peripheral b...

Background: One third of epileptic patients are resistant to several anti-epileptic drugs (AED). P-glycoprotein (P-gp) is an efflux transporter encoded by ATP-binding cassette subfamily B member 1 (ABCB1) gene that excludes drugs from the cells and plays a significant role in AEDs resistance. Over-expression of P-gp could be a result of polymorphisms in ABCB1 gene. We studied the association of...

This study aimed to appraise the chemical features such as total phenol (TP), total flavonoid (TF), total antioxidant capacity based on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays of bran and grain in 10 genotypes of rice (Oryza sativa L.) grown in Iran. Based on two procedures of DPPH and FRAP, the results demonstrated that in terms of the amount of...