A number of databases around the world currently host a wealth of genomic data that is invaluable to researchers conducting a variety of genomic studies. However, patients who volunteer their genomic data run the risk of privacy invasion. In this work, we give a cryptographic solution to this problem: to maintain patient privacy, we propose encrypting all genomic data in the database. To allow ...

BACKGROUND Familial aggregation and segregation analysis studies have provided evidence of a genetic basis for esophageal adenocarcinoma (EAC) and its premalignant precursor, Barrett's esophagus (BE). We aim to demonstrate the utility of linkage analysis to identify the genomic regions that might contain the genetic variants that predispose individuals to this complex trait (BE and EAC). METH...

CONTEXT Obesity is a growing health care problem worldwide and is a major underlying risk factor for common diseases such as diabetes. Parent-of-origin effect has been reported to be involved in the development of obesity. But the genes with imprinting effects related to obesity are largely unknown. OBJECTIVE The objective of the study was to identify obesity-related genetic loci, both with a...

Vegetables are an integral part of the human diet worldwide. Traditional breeding approaches have been used extensively to develop new cultivars vegetables with desirable characteristics, including resistance/tolerance biotic and abiotic stresses, high yield, elevated content compounds beneficial health. The technological progress since early 1980s has revolutionized our ability study manipulat...