AIM To evaluate fusidic acid resistance pheno- and geno-typically in nasal carriage Staphylococcus aureus isolated from general practice patients in nine European countries. MATERIALS & METHODS Phenotypic fusidic acid resistance was determined by disc diffusion and MIC values, and genotypically by a PCR detecting fusA-E genes. The main analysis was performed on methicillin-susceptible S. aure...

Job shop scheduling problem is one of the most important problems in the combinatorial optimization problems, and it is applied to various fields about engineering. Many works have been reported for this problem using Genetic Algorithm (GA). The GA is one of the most powerful optimization methods based on the mechanics of natural evolution. In this paper, we propose a new genetic coding for the...

Objective: To evaluate the correlation of TNF-α G308A polymorphism and heart disease (HD) using meta-analysis. Methods: Databases including PubMed, EMbase, CNKI and WanFang Data were searched (2003 to 2013). Results: A total of 5 studies were included, involving 539 heart disease (HD) cases and 624 controls. The results of meta-analysis according to recessive genetic model of TNF-α G308A showed...

Glinus lotoides. Linn is an ancient herb of India, generally known as Ciru-Ceruppadai, belonging to the family Molluginaceae. The natural plant resources and nature-derived chemical moieties are gaining the global demand to provide holistic health care to the Mankind. There is an indispensable need to explore the herbal resources to produce newer generation of drugs with great potential and min...

Hematopoietic stem cells (HSCs) maintain homeostasis and regenerate the blood system throughout life. It has been postulated that HSCs may be uniquely capable of preserving their genomic integrity in order to ensure lifelong function. To directly test this, we quantified DNA damage in HSCs and downstream progenitors from young and old mice, revealing that strand breaks significantly accrue in H...

BACKGROUND Papillomaviruses can cause proliferative skin lesions ranging from benign hyperplasia to squamous cell carcinoma (SCC). However, asymptomatic infection is also possible. Several groups have detected Felis domesticus Papillomavirus type 2 (FdPV2) DNA in association with feline Bowenoid in situ carcinoma (BISC). Therefore, a causative connection has been suggested. However, the knowled...

Prevention of environment- and gene-dependent, teratogenic malfunctions ("Functional Teratogenesis")-- caused by abnormal hormone, neurotransmitter and cytokine concentrations during organization of the neuro-endocrine-immune system (NEIS) should be considered as a global challenge of outstanding relevance. By optimizing the natural and social environment and correcting in time abnormal concent...