OBJECTIVE To determine the aetiology of genital ulcers and discharges in rural south western Uganda and to assess response to syndromic treatment. METHOD A longitudinal, prospective study using laboratory testing and questionnaires to evaluate 561 adult men and women presenting with clinically verified genital ulcers, urethral, or vaginal discharge at a general outpatient clinic and two healt...

OBJECTIVE The purpose of this study was to determine the cost-effectiveness of routine antenatal screening for herpes simplex virus 1 and 2 in women without a known history of genital herpes. STUDY DESIGN Decision analysis was used to compare 3 treatment strategies to prevent neonatal herpes infection in women without a known history of genital herpes simplex virus: (1) the current standard o...

Sir, Knowledge of the seroepidemiology of herpes simplex virus (HSV) infections is an important factor for estimating the risk of contracting genital herpes. Previous studies have shown that HSV-2 seropositivity correlates with past sexual activity and, as such, serves as a serological marker of sexual behaviour (1, 2). There has been a decline in HSV-2 seroprevalence in Denmark among blood don...

herpes simplex virus (hsv) is a worldwide contagious infection disease.  it usually transmitted during childhood via nonsexual contacts. one of the important causes of genital herpes in developed countries is hsvi. having knowledge about distribution and prevalence of this infection in pregnant women may help to choose an appropriate treatment and prevention methods. 65 pregnant women who have ...

The claim that circumcision reduces the risk of sexually transmitted infections has been repeated so frequently that many believe it is true. A systematic review and meta-analyses were performed on studies of genital discharge syndrome versus genital ulcerative disease, genital discharge syndrome, nonspecific urethritis, gonorrhea, chlamydia, genital ulcerative disease, chancroid, syphilis, her...

OBJECTIVE Genital herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases in the United States. Perinatal transmission of the virus to the fetus or neonate is a major concern in affected pregnancies. Our objective was to systematically review published data to estimate the effect of prophylactic acyclovir provided to pregnant women near term on the rat...

for Community-Acquired Pneumonia Speaker: John Pullman, MD, Infectious Diseases Specialist, Internal Medicine, Mercury Medical Center, Butte, Montana. Telithromycin (KetekTM, Aventis), administered once daily for five to ten days to patients with CAP, has been found to be as effective and safe as standard twice-daily, 10-day treatment with clarithromycin (Biaxin, Abbott), a commonly prescribed ...