to study genetic diversity and drought tolerance in sesame genotypes, an experiment in a randomized complete block design with three replications in 2010-2011 was conducted at the agricultural research field, university of birjand under stress and non-stress conditions. the aim of this study was the testing of yield, tolerance index and bi-plot analysis. materials included genotypes birjand, kh...

Yersinia spp. cause gastroenteritis and the plague, representing historically devastating pathogens that are currently an important biodefense and antibiotic resistance concern. A critical virulence determinant is the Yersinia protein kinase A, or YpkA, a multidomain protein that disrupts the eukaryotic actin cytoskeleton. Here we solve the crystal structure of a YpkA-Rac1 complex and find that...

Mammalian neuroglobin (Ngb) protects neuronal cells under conditions of oxidative stress. We previously showed that human Ngb acts as a guanine nucleotide dissociation inhibitor (GDI) for the α-subunits of heterotrimeric Gi/o proteins and inhibits the decrease in cAMP concentration, leading to protection against cell death. In the present study, we used an eukaryotic expression vector driving h...

The RhoGDI proteins serve as key multifunctional regulators of Rho family GTP-binding proteins. The 2.6 A X-ray crystallographic structure of the Cdc42/RhoGDI complex reveals two important sites of interaction between GDI and Cdc42. First, the amino-terminal regulatory arm of the GDI binds to the switch I and II domains of Cdc42 leading to the inhibition of both GDP dissociation and GTP hydroly...

Full Adder is the basic building block for various arithmetic circuits such as compressors, multipliers, comparators and so on. 1-bit Full Adder cell is the important and basic block of an arithmetic unit of a system. Hence in order to improve the performance of the digital computer system one must improve the basic 1-bit full adder cell. In this, Full Adder is designed by using Hybrid-CMOS log...

We introduce the Movement Deviation Profile (MDP), which is a single curve showing the deviation of an individual's movement from normality. Joint angles, recorded from typically developing children over one gait cycle, were used to train a self-organizing map (SOM) which then generated MDP curves for patients with gait problems. The mean MDP over the gait cycle showed a high correlation (r(2) ...

The objective of this study was to evaluate associations between cigarette smoking and socio-economic variable in an Iranian male population. Isfahan Healthy Heart Program (IHHP) is a community oriented health study from which we obtained our data regarding male subjects. Socio-demographic variables--sex, age, marital status, educational level, occupation, and income--and physical activity leve...

The energy efficiency of Gasoline Direct Injection (GDI) engines is leading to a continuous increase in GDI engine vehicle population. Consequently, their particulate matter (soot) emissions are also becoming concern. As required for diesel engines, meet the limits set by regulations, catalyzed filters considered as an effective solution through which soot could be trapped and burnt out. Howeve...

O objetivo desta pesquisa foi realizar a adaptação cultural e apresentar as evidências de validade do Growing Disciples Inventory (GDI) para língua portuguesa no Brasil cultura brasileira. Para esse trabalho, abordagem quantitativa utilizada Taxonomia COSMIN cultural, seguida da avaliação um comitê especialistas o pré-teste com aplicação inventário 42 adultos, universitários pessoas comunidade....