background and objectives: brucella, causative of brucellosis, has some potential virulence factors involved in brucella replication and its strategies to circumvent the immune response. one of them is the virb gene that encodes the type іv secretion system proteins (t4ss) involved in intracellular replication of organism. brucella virulence factor a ( bvf a), and urease ( ure ) has also been d...

a member of homeodomain protein namely tgif2lx has been implicated as a tumor suppressor gene in human malignancy as well as in spermatogenesis. however, to our knowledge, dynamic functional evidence of the tgif2lx has not yet been provided. the aim of the present study was to investigate the human tgif2lx target gene(s) using a cdna-aflp as a differential display method. a pegfp-tgif2lx constr...

current investigations indicate different in vitro infection patterns for oka and dumas strains. infection of cells in culture with dumas strain produces lower number of infectious particles while the oka strain is highly infectious in vitro. it is postulated that weak expression of the replication genes in dumas strain may be the reason for the attenuated phenotype. the objective of this stud...

the present investigation was conducted to study the effects of experimental clostridium perfringens type d enterotoxaemia in teddy goats. clinical signs started to appear after 30 min of experimental infection like anorexia, diarrhea, dehydration, frothing and dyspnea. gross lesions consisted of severe congestion in tissues of varying intensity with enlarged mesenteric lymph nodes while histol...

background and aims: the aim of this study was to determine the virulence and antibiotic resistance properties of streptococcus agalactiae (s. agalactiae) and streptococcus uberis (s. uberis) isolated from the ruminant’s sub-clinical mastitic milk in iran. materials and methods: positive samples in the cmt test were cultured and s. agalactiae and s. uberis have been identified using biochemical...

background: acinetobacter spp. is characterized as an important nosocomial pathogen and increasing antimicrobial resis­tance. our aim was to evaluate antimicrobial susceptibility and aminoglycosides resistance genes of acinetobacter spp. iso­lated from hospitalized patients. methods: sixty isolates were identified as acinetobacter species. the isolates were tested for antibiotic resistance by d...

transition from vegetative to reproductive growth is an important stage in plant’s life. flowering pathways including photoperiod, vernalization, gibberellins, and autonomous pathway are regulated by different genes. identification of flowering genes is essential for the development of bolting-resistant sugar beet cultivars. in this study, a set of 118 arabidopsis thaliana genes involved in flo...

Pertussis is still endemic and the recently resurgence of the disease caused by Bordetella pertussis has been shown in many countries. The polymorphism of the virulence genes of B. pertussis and lack of any information about the allelic variation between the Iranian isolates promotes us to analysis of the genes encoded virulence factors including ptxS1, prn, fim3 and cya to understand the diffe...