There is considerable debate on whether the employment and earnings prospects are better for those on low pay or for the unemployed. We use Understanding Society data for England and estimate dynamic random effects panel models which show robust evidence that the future unemployment risk is lower for those who are currently on low pay compared to those who are currently unemployed and the low-p...

A new type of feedback is presented that involves both the auditory and visual modalities. It combines an audio resonant bandpass filter, a geometrically constructed mass-spring system and its graphical skin. The system shows a resonant behavior that is detailed in various parameter setups. Complex mass-spring topologies result in a coherent self-sustained audio-visual system that mimics gusts ...

W propose a measure of managerial ability, based on managers’ efficiency in generating revenues, which is available for a large sample of firms and outperforms existing ability measures. We find that our measure is strongly associated with manager fixed effects and that the stock price reactions to chief executive officer (CEO) turnovers are positive (negative) when we assess the outgoing CEO a...

We describe an approach to building models for data with random effects. The modeling includes both random location effects and random scale effects. The approach consists of a sequence of steps. In each step, model building tools based on certain statistics are used to study the structure of the data and identify or check an aspect of the model; the results of most of the steps are used explic...

The bioavailability of methylmercury (MeHg) in the brains of  orange spotted groupers, captured from four creeks of Mahshahr embayment was measured.  Then the effects of this pollutant on the regulation of gene expression, acetylcholinesterase transcript levels was chosen in order to monitor the amounts of methylmercury concentrations in the creeks, and the fluctuations of mRNA expressions in t...

Abstract Background Hypertrophic cardiomyopathy (HCM) has long been described as the archetypal monogenic cardiac disease. It fulfils criteria for Mendelian inheritance and painstaking early co-segregation studies by Seidman et al in 1990 lead to discovery that mutations MYH7 cause HCM. From here, genetic architecture of HCM gradually assembled thousands individual discovered. The complexity ge...

Neuroendocrine systems play a key role not only in the maintenance of whole-body homeostasis but also as the link between behavioural, endocrine and autonomic responses to environmental stimuli. It is becoming increasingly clear that neuroendocrine regulatory mechanisms are under the control of a combination of factors including genetic background, environment and early-life programming. Patter...

The objectives of this article are twofold: (a) to outline the basic concepts associated with the linear mixed model and (b) to illustrate how this model can be used to analyse systematic interindividual differences in intraindividual change, this being achieved through a longitudinal study of a cohort of children living in Cordoba (Argentina). These objectives will be met by using the PROC MIX...

ABSTRACT The SAS ® procedure MIXED provides a single tool for analyzing a large array of models used in statistics, especially experimental design, through the use of REML estimation. A strategy for identifying mixed models is followed by a description of REML estimation along with a simple example that illustrates its advantages. A comparison of some of the available tests for variance compone...