China’s and Europe’s dependence on imported protein is a threat to the food self-sufficiency of these regions. It could be solved by growing more legumes, including alfalfa that highest producer under temperate climate. To create productive high-value varieties, use large genetic diversity combined with genomic evaluation improve current breeding programs. study diversity, we have used set 395 ...

Abstract Over the past 20 years, introduction of new molecular techniques has given a impetus to genetic and genomic studies fishes. The main traits selected in aquaculture sector conform polygenic model, and, thus far, effective breeding programmes based on genome-wide association (GWAS) marker-assisted selection (MAS) have been applied simple (e.g. disease resistance sexual maturation salmoni...

Abstract Background Improving yield prediction and selection efficiency is critical for tree breeding. This vital macadamia trees with the time from crossing to production of new cultivars being almost a quarter century. Genomic (GS) useful tool in plant breeding, particularly perennial trees, contributing an increased rate genetic gain reducing length breeding cycle. We investigated potential ...

A common problem for genome-wide association analysis (GWAS) is lack of power for detection of quantitative trait loci (QTLs) and precision for fine mapping. Here, we present a statistical method, termed single-step GBLUP (ssGBLUP), which increases both power and precision without increasing genotyping costs by taking advantage of phenotypes from other related and unrelated subjects. The proced...

Genomic prediction exploits single nucleotide polymorphisms (SNPs) across the whole genome for predicting genetic merit of selection candidates. In most models for genomic prediction, e.g. BayesA, B, C, R and GBLUP, independence of SNP effects is assumed. However, SNP effects are expected to be locally dependent given the presence of a nearby QTL because SNPs surrounding the QTL do not segregat...

BACKGROUND The QTLMAS XVth dataset consisted of the pedigrees, marker genotypes and quantitative trait performances of 2,000 phenotyped animals with a half-sib family structure. The trait was regulated by 8 QTL which display additive, imprinting or epistatic effects. This paper aims at comparing the QTL mapping results obtained by six participants of the workshop. METHODS Different regression...

Estimated breeding values (EBVs) and genomic enhanced breeding values (GEBVs) for milk production of young genotyped Holstein bulls were predicted using a conventional BLUP - Animal Model, a method fitting regression coefficients for loci (RRBLUP), a method utilizing the realized genomic relationship matrix (GBLUP), by a single-step procedure (ssGBLUP) and by a one-step blending procedure. Info...

The genomic relationship matrix (GRM) can be inverted by the algorithm for proven and young (APY) based on recursion on a random subset of animals. While a regular inverse has a cubic cost, the cost of the APY inverse can be close to linear. Theory for the APY assumes that the optimal size of the subset (maximizing accuracy of genomic predictions) is due to a limited dimensionality of the GRM, ...

Introduction Litter size in pigs has increased steadily since 1990. Because of unfavorable genetic correlations with piglet mortality, breeding goals should include survival traits next to litter size. Unbalanced programs that neglect this requirement have produced mortality levels, attracting negative public attention. Balanced does not disadvantage, but the general is largely unaware this. Me...