Several cytokines or growth factors induce macrophages to proliferate, become activated, differentiate, or die through apoptosis. Like the major macrophage activator IFN-gamma, the extracellular matrix protein decorin inhibits proliferation and protects macrophages from the induction of apoptosis. Decorin enhances the IFN-gamma-induced expression of the IAalpha and IAbeta MHC class II genes. Mo...

Lemur beta-related globin genes have been isolated and sequenced. Orthology of prosimian and human epsilon-, gamma-, and beta-related globin genes was established by dot-matrix analysis. All of these lemur globin genes potentially encode functional beta-related globin polypeptides, though precisely when the gamma-globin gene is expressed remains unknown. The organization of the 18-kb brown lemu...

i131 is a famous radio-iodine isotope in use for diagnosis and treatment of hyper functioning and cancerous thyroid gland. it is a nuclear reactor product; however nuclear reactor may be unavailable in some areas. replacement by i-124 may be possible, another iodine isotope producible by cyclotron; a system more available than reactor. here absorbed fraction of gamma and beta rays of i-124 thro...

Among the extracellular signals that modulate the synthesis of collagen, transforming growth factor-beta (TGF-beta) and interferon-gamma (IFN-gamma) are preeminent. These two cytokines exert antagonistic effects on fibroblasts, and play important roles in the physiologic regulation of extracellular matrix turnover. We have shown previously that in normal skin fibroblasts, TGF-beta positively re...

Connective tissue growth factor (CCN2) is a profibrotic factor acting downstream and independently of TGF-beta to mediate renal fibrosis. Although inflammation is often involved in the initiation and/or progression of fibrosis, the role of inflammatory cytokines in regulation of glomerular CCN2 expression, cellular proliferation, and extracellular matrix accumulation is unknown. We studied two ...

A $Gamma$-so-ring is a structure possessing a natural partial ordering, an infinitary partial addition and a ternary multiplication, subject to a set of axioms. The partial functions under disjoint-domain sums and functional composition is a $Gamma$-so-ring. In this paper we introduce the notions of subdirect product and $(phi,rho)$-product of $Gamma$-so-rings and study $(phi,rho)$-represen...

New upper bounds are developed for the $L_2$ distance between $\xi/\text{Var}[\xi]^{1/2}$ and linear quadratic functions of $z\sim N(0,I_n)$ random variables form $\xi=bz^\top f(z) - \text{div} f(z)$. The approximation yields a central limit theorem when squared norm $f(z)$ dominates Frobenius $\nabla f(z)$ in expectation. Applications this normal given asymptotic normality de-biased estimators...

The Be stars display variable optical emission lines originating in the circumstellar disc. Here we analyse high resolution spectroscopic observations of and distance between peaks H-alpha, H-beta, H-gamma ($\Delta V_\alpha$, $\Delta V_\beta$, V_\gamma$ respectively). Combining published data, spectra from ELODIE archive (obtained period 1998 -- 2003) Rozhen 2015 2023) 93 stars, find a set rela...