Abstract This paper reports the development and detailed properties of about 13 metric tons gadolinium sulfate octahydrate, $\rm Gd_2(\rm SO_4)_3\cdot \rm 8H_2O$, which has been dissolved into Super-Kamiokande (SK) in summer 2020. We evaluate impact radioactive impurities 8H_2O$ on diffuse supernova neutrino background searches solar observation confirm need to reduce fluorescent by three order...

Background Gadolinium-enhanced CMR can be a useful adjunct in the diagnosis and assessment of acute myocardial infarction (AMI). However, gadolinium contrast is contraindicated in severe renal impairment. Alternative, non-gadolinium contrast agents for AMI assessment and contrast-enhanced CMR in general would be of substantial clinical importance. Ferumoxytol, an intravenous iron-supplementatio...

Gravid macaques (n=12) were maintained on a control diet (14% calories from fat, n=4) or a high fat diet (36% calories from fat, n = 8). On gestational day 129, the macaques were injected with ProHance gadolinium contrast for placental imaging (equivalent to the third trimester). Gadolinium dose was varied based on maternal weight, using 0.1 mmol/kg dosing. Fetuses were delivered via cesarean s...

a o t I o c t Gadolinium-based extracellular contrast agents have enabled cardiac magnetic resonance (CMR) to assess viability and fibrosis at a higher resolution than alternative technologies (1). In this issue of iJACC, Matsumoto et al. (2), present convincing data that early contrast enhancement approximately 2 min after administration of gadolinium depicts the area at risk associated with a...

a t e M d f t m i n m d s a w ( T In 1794, Johan Gadolin, a Finnish scientist, isolated a new rare earth metal from a black, heavy mineral found at a quarry on an island near Stockholm. Originally named ytterbia, in honor of the nearby village, the substance soon acquired the name gadolinite in honor of Johan, and subsequently gadolinium. Gadolin’s surname, the Hebrew word for “great,” was chos...

Two dialysis-dependent patients with end-stage renal disease underwent brain and spine MR imaging a few days after having undergone gadolinium-enhanced imaging studies. Increased signal intensity in the subarachnoid space on T1-weighted and fluid-attenuated inversion recovery images was noted. Excretion of gadolinium into the CSF was proven in one case by mass spectrometry. Dialysis-dependent p...