This study used Nelore embryo donors to evaluate the effects of summer temperatures and humidity in a tropical area on embryo recovery. Seventeen cows were randomly assigned to three groups (G1, G2 and G3) as well as 28 heifers into four groups (G4, G5, G6 and G7), and underwent a consecutive 4 days superovulation protocol (day 0 to 3) and two artificial inseminations (AI; day 4 and 5). Cortiso...

The aim of this study was to determine the most appropriate months for applying albendazole (ABZ; oral suspension dose 20 mg/kg body weight) to sheep naturally infected with Dicrocoelium dendriticum and kept at pasture, in order to reduce parasite egg shedding to a minimum, mainly during the cold months and, as a result, decrease pasture contamination by viable eggs. Five animal groups (G), hom...

Poly(amidoamine) (PAMAM) dendrimer nanoparticles have been demonstrated to elicit a well defined cytotoxicological response from mammalian cell lines, the response increasing systematically with dendrimer generation and number of surface amino groups. In this work, using generation G4, G5, and G6 dendrimers, this systematic response is furthermore demonstrated for the generation of reactive oxy...

Background: In the recent years, pregnancy outcomes in women with primary chronic glomerulonephritis (CGN) have been encouraging despite increased incidence of complications and preterm birth. However, impact on CKD progression remains understudied.
 Aim: To evaluate effect postpartum period patients CGN.
 Materials methods: This was an observational longitudinal study. The study grou...

HLA-G is a non-classical MHC class I antigen that functions as an immunomodulatory molecule. There are two forms of HLA-G antigens, soluble and membrane bound. Soluble HLA-G can be produced by translation of HLA-G transcripts (HLA-G5, -G6, -G7) and by shedding/proteolytic cleavage of membrane bound antigens (HLA-G1, -G2, -G3, -G4). Soluble as well as membrane bound HLA-G molecules have a direct...

Acute rejection (AR) is a strong risk factor for chronic rejection in renal transplant recipients. Accurate and timely diagnosis of AR episodes is very important for disease control and prognosis. Therefore, objectively evaluated the immune status of patients is essential in the field of post-transplantation treatment. This longitudinal study investigated the usefulness of five biomarkers, huma...

BACKGROUND We report here a unique approach to using multifunctional dendrimer/combretastatin A4 (CA4) inclusion complexes for targeted cancer therapeutics. METHODS Amine-terminated generation 5 polyamidoamine dendrimers were first partially acetylated to neutralize a significant portion of the terminal amines, and then the remaining dendrimer terminal amines were sequentially modified with f...

Although many breast and lung cancers overexpress human epidermal growth factor receptor-2 (HER-2), no methods currently exist for effective and early detection of HER-2-positive cancers. To address this issue, we designed and synthesized dendrimer-based novel nano-imaging agents that contain gold nanoparticles (AuNPs) and gadolinium (Gd), conjugated with the humanized anti-HER-2 antibody (Herc...

A new phosphor, Sm3+ ion-doped YInGe₂O₇, was synthesized using a planetary ball mill solid state reaction. The XRD patterns show that all of the peaks can be attributed to the monoclinic YInGe₂O7 crystal structure when the Sm3+ ion concentration is increased up to 20 mol %. Under an excitation wavelength of 404 nm, the Sm3+ intra-4f transition appears in the emission spectrum including two stro...