Emerging evidence suggests that renal endothelial function may be altered in ischemia-reperfusion injury. Acute kidney injury is sexually dimorphic, and estrogen protects renal tubular function after experimental ischemic injury. This study tested the hypothesis that during ischemia-reperfusion, estrogen alters glomerular endothelial function to prevent hyperpermeability. Glomerular endothelial...

BACKGROUND Osteoporosis is associated with 17β-estradiol deficiency. The G protein-coupled receptor 30 (GPR30) is known to be an estrogen-responsive receptor, but its role in the degradation of mitochondria in osteoblasts by autophagy, or mitophagy, remains unclear. The aim of this in vitro study was to evaluate the effects of 17β-estradiol, GPR30, and its signaling pathway, on mitophagy in the...

G protein-coupled receptor (GPR) 30 is a novel estrogen receptor. Recent studies suggest that activation of the GPR30 confers rapid cardioprotection in isolated rat heart. It is unknown whether chronic activation of GPR30 is beneficial or not for heart failure. In this study we investigated the cardiac effect of sustained activation or inhibition of GPR30. Female Sprague-Dawley rats were divide...

ABSTRACT We examine how investment professionals assess the usefulness of financial accounting information depending on their acquisition objectives and preparers' earnings management incentives. conduct a survey experiment based face-to-face interviews with document two main results. First, we find that, compared assigned firm valuation objective, those managerial performance evaluation object...

This study contributes to the literature on energy market risk management and portfolio by examining co-movements between several commodities in a context light of impact types uncertainty over time under high, medium, low frequencies. Using wavelet decomposition analysis, we first investigate lead-lag relationship together with power correlation major renewable non-renewable indexes indexes. S...

Abstract Objective: To study the effect of an 830-nm gallium-aluminum-arsenic (GaAlAs) diode laser at two different energy densities (5 and 15 J/cm(2)) on the epiphyseal cartilage of rats by evaluating bone length and the number of chondrocytes and thickness of each zone of the epiphyseal cartilage. Background Data: Few studies have been conducted on the effects of low-level laser therapy on th...

BACKGROUND AND PURPOSE Recent evidence indicates that GPER (G protein-coupled oestrogen receptor 1) mediates acute pre-ischaemic oestrogen-induced protection of the myocardium from ischaemia/reperfusion injury via a signalling cascade that includes PKC translocation, ERK1/2/ GSK-3β phosphorylation and inhibition of the mitochondrial permeability transition pore (mPTP) opening. Here, we investig...

The outbreak of the COVID-19 pandemic has hit global financial markets, including energy commodities. aim paper is to examine reaction commodity market pandemic, particularly epidemic status, stringency government anti-COVID-19 policy, and stock volatility. We use daily data on S&P GSCI Energy index, number new confirmed cases, self-developed Global Stringency Index, VIX index. research cov...

This article examines the structural responses of foreign exchange and equity markets to COVID-19 pandemic in seven Asian countries over its first 4 months (31 December 2019 1 May 2020). Marginal effects derived from a vector autoregression (SVAR) model suggest that 1% increase incidence cases significantly diminished Indonesia’s market returns by 4.7%, depreciated Indian rupee against US dolla...

The present study aimed to evaluate productive characteristics and the physical, chemical sensory quality of juices elaborated from different genotypes ‘Bordô’ cv. produced in Vale do Rio Peixe-SC region, 2016/17. 11 clones evaluated were identified as: G03, G07, G08, G10, G12, G13, G15, G16, G17, G18 G19. At harvest, fruit production evaluated. mean productivity tested was 31.2 t ha-1, with a ...