The diagnosis and treatment of central nervous system fungal infections typically pose problems for the clinician. With an increased incidence of fungal infections in immunocompromised patients, neuroradiologic imaging has become essential in determining complications and outcomes. This article provides a summary of the more common organisms encountered in fungal infections of the central nervo...

Estimates of the incidence and prevalence of serious fungal infections, based on epidemiological data, are essential in order to inform public health priorities given the lack of resources dedicated to the diagnosis and treatment of these serious fungal diseases. However, epidemiology of these infections is largely unknown, except for candidaemia and cryptococcosis. The aim of this work is to c...

The impact of the AIDS epidemic is already severe and continues to increase over the next decades. Many of the fungal infections are opportunistic infections among HIV/AIDS patients. People with weakened immune system are more vulnerable to fungal infections. The aim of the study is to find the prevalence of dermatological manifestation related to fungal infections among HIV patients and its co...

Fungal infections of the central nervous system (CNS) evoke humoral and cellular immune responses with the scope to enable the host to eliminate the pathogen. Immunopathogenesis of CNS fungal infections remains incompletely understood, with most of our understanding coming from studies on experimentally infected animals. However, activation of brain resident cells combined with relative express...

While fungal infections of the central nervous system (CNS) are relatively rare, fungal pathogens are increasingly being recognized as an important etiology of CNS infections, particularly amongst the growing immunocompromized population. In this paper we aim to provide a practical approach to the diagnosis of fungal infections of the CNS, review some of the diagnostic methods currently availab...

Infections are an important issue in systemic lupus erythematosus (SLE) patients and account for 30-50% of mortality and morbidity [1-5]. Both cellular and humoral immunity defects [6] and the use of corticosteroids and immunosuppressant agents [7,8] make these patients more susceptible to pathogens. Most infectious processes result from common microorganisms such as bacteria and viruses [9]. I...

fungal infections of the gastrointestinal tract are not common in children, especially in immunocompetent ones. in this case report we describe a child who was presented with abdominal pain and mass, bloody diarrhea and fever. he was treated for amebiasis, but due to treatment failure and deterioration of his condition, he underwent a laparatomy. histologic examination of the excised bowel in t...

Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10 million serious allergies and more than a million deaths each year. Global mortality owing to fungal infections is greater than for malaria and breast cancer and is equivalent to that owing to tuberculosis (TB) and HIV. These statistics evidence fungal infections as a major threat to human health and a...

Prevalence of superficial and systemic mycoses has increased in recent years. The most common etiological factors responsible for those infections are fungi of the genus Candida, mainly Candida albicans; however approximately 35–65% of candidemia cases are caused by other species of this particular genus, described in literature as Candida non-albicans pathogens. Fungal infections have deleteri...