نتایج جستجو برای: fto
تعداد نتایج: 1986 فیلتر نتایج به سال:
Reducing the energy loss and retarding the carrier recombination at the interface are crucial to improve the performance of the perovskite solar cell (PSCs). However, little is known about the recombination mechanism at the interface of anode and SnO2 electron transfer layer (ETL). In this work, an ultrathin wide bandgap dielectric MgO nanolayer is incorporated between SnO2:F (FTO) electrode an...
Flourine doped tin oxide thin films have been prepared on glass substrate by spin coating method via sol-gel route. The rheological behavior of the prepared sol solution has been studied by viscosity measurement and from this, the optimum coating period has been investigated and reported. The films have been developed with fixed dopant concentration (F/Sn ratio 7.5 at %), under optimized operat...
BACKGROUND FTO variants are robustly associated with obesity and related traits in many population and shown to have variable impact during life course. Although studies have shown association of FTO variants with adiposity in adult Indian, its association in Indian children is yet to be confirmed. METHODS Here we examined association of FTO variants (rs9939609 and rs8050136) with obesity and...
BACKGROUND Children with rs9939609 FTO variant alleles (homozygous = AA and heterozygous = AT) are predisposed to greater adiposity than are those with 2 wild-type alleles (TT). OBJECTIVE Because FTO is highly expressed in hypothalamic regions that are important for appetite, FTO genotype may affect energy balance by influencing eating behavior. Loss of control (LOC) eating, a behavior common...
AIMS A common variant, rs9939609, in the FTO (fat mass and obesity) gene is associated with adiposity in Europeans, explaining its relationship with diabetes. However, data are inconsistent in South Asians. Our aim was to investigate the association of the FTO rs9939609 variant with obesity, obesity-related traits and Type 2 diabetes in South Asian individuals, and to use meta-analyses to attem...
زمینه و هدف: مطالعات وابستگی گسترده ژنومی تشخیص دادهاند که پلی مورفیسمهای ژن FTO با خطر دیابت نوع 2 و چاقی مرتبط است با این حال نتایج در مطالعات دیگر در جمعیتهای مختلف در این زمینه متناقض است، هدف مطالعه ما بررسی ارتباط پلی مورفیسم rs16953002 ژن FTO با دیابت و چاقی در جمعیت شهر یزد بود. مواد و روشها: افراد مورد مطالعه شامل 200 فرد کنترل و 200 فرد مبتلا به دیابت نوع 2 که به طور کاملا تصادفی از ...
Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...
In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with obesity in humans. Since then, various animal models have served to establish the mechanistic basis behind this association. Many earlier studies focussed on FTO's effects on food intake via central mechanisms. Emerging evidence, however, implicates adipose tissue development and function in the c...
OBJECTIVE Variation in the fat mass and obesity-associated (FTO) gene influences susceptibility to obesity. A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We examined the role of the FTO polymorphism rs8044769 in risk of knee and hip OA in cases and controls incorporating body mass index (BMI) information. METHODS 5409 knee OA patients, 4355 hip OA patie...
OBJECTIVE Polymorphisms in intron 1 of the 'fat mass and obesity-associated' (FTO) gene are associated with weight status. We hypothesized that the risk allele at a polymorphism in intron 1 of FTO is associated with weight regain after end of lifestyle intervention. METHODS We longitudinally analyzed the changes of weight status as BMI-SDS in 346 unrelated overweight children (mean age 10.6 ±...
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