The present investigation was carried out to determine the antioxidant properties in methanolic extract of leaves, stem, fruit and roots of Physalis angulata (L). The antioxidant assay was carried out using free radicals DPPH, superoxide, nitric oxide, hydrogen peroxide and hydroxyl radical. Among the extracts tested fruit and leaf extracts were found to be significant in their antioxidant prop...

the objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of cucumis melo in human prostate cancer cell line (pc-3) using mttand neutral red assays. the crude aqueous extract of c.melo was prepared by cold maceration method, filtered,concentrated and tested on pc-3 cell line. dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma pc-3 cell l...

This study was undertaken to investigate the toxicological profile of a methanolic extract of Garcinia pedunculata fruit in rats by conducting hematological, biochemical, and histopathological examinations. Long Evans rats were divided into four groups, each with 6 animals, and were treated with three oral doses (250, 500, and 1000 mg/kg) once daily for 21 days. The extract did not cause signif...

Two new dibenzocyclooctene lignans, neglschisandrins A-B (1-2), were isolated from the stems of Schisandra neglecta. Their structures and stereochemistries were elucidated by spectroscopic methods, including 1D- and 2D-NMR and HR-ESI-MS techniques.

The present study was designated to evaluate the antimicrobial activities of various solvent extracts from fruits of Terminalia chebula. The preliminary antimicrobial activities of the extracts against cariogenic organisms were tested by using disc diffusion assay. The methanolic extract showed higher antimicrobial activity against all the cariogenic organisms tested. Based on this finding, the...

Objectives: The natural origin of medicinal plants does not guaranteed their safety, as there are no sufficient studies on the safety, efficacy and toxicity to support their beneficial claims. Hence, this study aimed at investigating the oral acute toxicity of Adansonia digitata L. fruit shell extract on mice. Methods: Maceration method was employed for the extraction of Adansonia digitata fru...

Emblica officinalis Gaertn. (Euphorbiaceae) [EO] fruit is traditionally used as a general health tonic in Ayurveda. In the present study the effect of alcoholic extract of EO fruits was evaluated on acute stress induced biochemical and psychological changes in mice. Acute stress was induced by restraint stress method and the effect of EO at the doses of 100, 250 and 500mg/kg was evaluated on le...

The study was aimed to evaluate the carminative and antacid properties of Cucumis sativus fruit pulp aqueous extract under simulated conditions. Fresh fruit pulp of Cucumis sativus was homogenized and dried under shade and thus mass obtained was powdered, weighed and subjected for the evaluation of carminative and antacid profile of the drug. Carminative & antacid properties of Cucumis sativa w...