Haemagglutination of bluetongue virus (BTV) was demonstrated for the first time by making use of a purified preparation of the virus. The reaction was found to be independent of variations in the pH, temperature, buffer system and origin of the erythrocytes used in the test. A haemagglutination inhibition test, subsequently developed, was demonstrated to be serotype specific. The storage of the...

The characterization of the microstructures of freeze-dried food products determines the speed of and the properties after rehydration. The pore size distribution is an important characteristic of such textures. Spatial homogeneity and the orientation of voids and cracks inside the samples are studied.

Citation: Haggag YA and Faheem AM (2015) Evaluation of nano spray drying as a method for drying and formulation of therapeutic peptides and proteins. The high sensitivity of peptides and proteins to physicochemical stresses during processing and storage is the major hurdle against its pharmaceutical applications. Peptide-based drug formulations are commonly prepared as solid dosage forms becaus...

In 1890 Alt man dried pieces of frozen tissue by placing ¡hem in a vacuum desiccator at —20 °C. Since then the freeze drying technique has been constantly improved. In ¡939 the freeze drying process was placed for the first time on an engineering basis, and 1940 saw the large-scale production of dried plasma for wartime use. The first book unfreeze drying by Flosdorfin 1949 was followed by the ...

Cold pressed peel oil was added to high quality 50°Brix commercial orange concentrate and foam-mat dried, or diluted to single strength juice and freeze-dried using different platen temperatures. Amounts of peel oil ranged from 0.026% to 0.106% for samples to be foam-mat dried, and from 0.011% to 0.109% for freeze drying. For foam-mat drying, previously de veloped standard commercial conditions...

Staphylococcus aureus phage ISP was lyophilized, using an Amsco-Finn Aqua GT4 freeze dryer, in the presence of six different stabilizers at different concentrations. Stability of the lyophilized phage at 4 °C was monitored up to 37 months and compared to stability in Luria Bertani broth and physiological saline at 4 °C. Sucrose and trehalose were shown to be the best stabilizing additives, caus...

The stability of prothrombin and factor VII was studied using accelerated degradation tests in three preparations of freeze-dried pooled normal plasmas. In a previous report (Brozović, Gurd, Robertson, and Bangham, 1971) factor X was shown to be relatively unstable in these preparations of freeze-dried plasma: it was calculated that up to 8% of the original factor X activity would be lost after...

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We studied the effect of lyophilization of serum pools on the determination of cholesterol with the enzymatic methods used in five automated analyzers: SMAC (Technicon), the RA-1000 (Technicon), the aca (Du Pont), the TDx (Abbott), and the Ektachem 700P (Kodak). We prepared two serum pools: pool A (2.2 g/L) and pool B (1.9 g/L). We separated each pool into three groups for treatment by lyophili...

Abstract In this work, the advantages and disadvantages of freeze drying microwave were considered analyzed. Experimental data on plums are given. The chemical composition before after freeze-drying was results moisture change, compared.