Mechanical unfolding of the fourth domain of Distyostelium discoideum filamin (DDFLN4) was studied in detail using the C(alpha)-Go model. We show that unfolding pathways of this protein depend on the pulling speed. The agreement between theoretical and experimental results on the sequencing of unfolding events is achieved at low loading rates. The unfolding free energy landscape is also constru...

Existence of capacity drop phenomenon, as the difference between pre-queue and queue discharge flow rates, has been one of the controversial concepts of traffic engineering. Several researches have focused on capacity drop existence and also its estimation issues. This paper aims to estimate capacity drop based not only on a comparison between breakdown and queue discharge flow rates, but also ...

The nonequilibrium work relation allows for the calculation of equilibrium free energy differences between states based on the exponential average of accumulated work from irreversible transitions. Here, we compare two distinct approaches of calculating free energy surfaces from unidirectional single-molecule pulling experiments: the stiff spring approximation and the Hummer-Szabo method. First...

The energetics of driven magnetic reconnections induced by the deformation of the magnetopause boundary due to the solar wind-magnetosphere interaction are studied. The bursty type reconnection ensues due to the forcing of the magnetopause boundary by the solar wind. For typical plasma parameters in the inner central plasma sheet (ICPS), the magnetic energy release during the reconnection is es...

We study, in the fluid flow framework, the cooperative dynamics of a buffered production line in which the production rate of each work-cell does depend on the content of its adjacent buffers. Such state dependent fluid queueing networks are typical for people based manufacturing systems where human operators adapt their working rates to the observed environment. We unveil a close analogy betwe...