نتایج جستجو برای: fragility
تعداد نتایج: 8121 فیلتر نتایج به سال:
BACKGROUND Fractures associated with bone fragility in older adults signal the potential for secondary fracture. Fragility fractures often precipitate further decline in health and loss of mobility, with high associated costs for patients, families, society and the healthcare system. Promptly initiating a coordinated, comprehensive pharmacological bone health and falls prevention program post-f...
Context: Primary hyperparathyroidism (PHPT) is commonly associated with reduced bone mineral density (BMD) presenting with osteoporosis, increasing the risk of bone fragility fractures in these patients. Bisphosphonates, due to their anti-resorptive action, are known to improve the BMD and reduce the risk of bone fragility fractures. Therefore, bisphosphonates are considered as an alternative t...
Strategies to reduce fracture risk must be based on the understanding of the mechanisms that underline the increased incidence of fractures with age and with bone diseases that reduce bone stock. There is evidence that in addition to bone minerals density, other factors influence bone strength. This study reviews the biomechanical aspects of age-related fractures, including the interacting role...
Fragile sites are heritable specific chromosome loci that exhibit an increased frequency of gaps, poor staining, constrictions or breaks when chromosomes are exposed to partial DNA replication inhibition. They constitute areas of chromatin that fail to compact during mitosis. They are classified as rare or common depending on their frequency within the population and are further subdivided on t...
We report an original method that provides a new insight into the reaction mechanism by direct observation of bond breaking and formation. Variations of the diagonal elements of the Hessian along the IRC are shown to reflect the anharmonic properties of the system that are induced by electron density modifications upon the reaction. This information is presented in the form of the reaction spec...
I develop a framework of the build-up and outbreak of financial crises in an asymmetric information setting. In equilibrium, two distinct economic states arise endogenously: normal times – periods of modest investment, and booms – periods of expansionary investment. Normal times occur when the intermediary sector realizes moderate investment opportunities. Booms occur when the intermediary sect...
in this paper, efforts are made to compare the safety of steel moment resistant frames designed according to different editions of the iranian code of practice for seismic resistant design of buildings. also, failure risk of a low and medium height frame which designed for high and low seismicity regions according to three editions of the code are evaluated. first, the testing cases were design...
I T HAD BEEN ESTABLISHED by previous observations”2 that heating normal human red blood cells increases their osmotic and mechanical fragiities, and results in their sequestration in the spleen37 and liver.8 Human erythrocytes undergo budding, and the heated red cells subdivide into fragments having a decreased ratio of surface volume and increased osmotic fragility.’ Kimber and Lander8 have sh...
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