نتایج جستجو برای: fractional flow reserve

تعداد نتایج: 563105  

Journal: :Circulation 1999
C E Hanekamp J J Koolen N H Pijls H R Michels H J Bonnier

BACKGROUND Although intravascular ultrasound (IVUS) is the present standard for the evaluation of optimum stent deployment, this technique is expensive and not routinely feasible in most catheterization laboratories. Coronary pressure-derived myocardial fractional flow reserve (FFRmyo) is an easy, cheap, and rapidly obtainable index that is specific for the conductance of the epicardial coronar...

Journal: :Journal of the American College of Cardiology 1998
G J Bech B De Bruyne H J Bonnier J Bartunek W Wijns K Peels G R Heyndrickx J J Koolen N H Pijls

OBJECTIVES This study sought to determine the safety of deferral of percutaneous transluminal coronary angioplasty (PTCA) of angiographically intermediate but functionally nonsignificant stenosis, as assessed by coronary pressure measurement and myocardial fractional flow reserve (FFRmyo). BACKGROUND Decision making in patients with chest pain and intermediate coronary stenosis remains diffic...

2015
Zixin Deng Qi Yang Xiaoming Bi Zhaoyang Fan Debiao Li

Background Fractional Flow Reserve (FFR) is an invasively determined index of the functional severity of an intermediate coronary stenosis by measuring the pressure drop across the lesion [1]. Noninvasive pressure gradient (ΔP) measurements using phase-contrast (PC)-MRI have been attempted in the aorta, carotid, and renal arteries [2-4]. The purpose of this study is to assess the reproducibilit...

Journal: :Circulation. Cardiovascular interventions 2014
Ricardo Petraco Tim P van de Hoef Sukhjinder Nijjer Sayan Sen Martijn A van Lavieren Rodney A Foale Martijn Meuwissen Christopher Broyd Mauro Echavarria-Pinto Nicolas Foin Iqbal S Malik Ghada W Mikhail Alun D Hughes Darrel P Francis Jamil Mayet Carlo Di Mario Javier Escaned Jan J Piek Justin E Davies

BACKGROUND Coronary flow reserve has extensive validation as a prognostic marker in coronary disease. Although pressure-only fractional flow reserve (FFR) improves outcomes compared with angiography when guiding percutaneous coronary intervention, it disagrees with coronary flow reserve classification 30% of the time. We evaluated whether baseline instantaneous wave-free ratio (iFR) could provi...

Journal: :Circulation 2016
Julien Adjedj Bernard De Bruyne Vincent Floré Giuseppe Di Gioia Angela Ferrara Mariano Pellicano Gabor G Toth Jozef Bartunek Marc Vanderheyden Guy R Heyndrickx William Wijns Emanuele Barbato

BACKGROUND The fractional flow reserve (FFR) value of 0.75 has been validated against ischemic testing, whereas the FFR value of 0.80 has been widely accepted to guide clinical decision making. However, revascularization when FFR is 0.76 to 0.80, within the so-called gray zone, is still debatable. METHODS AND RESULTS From February 1997 to June 2013, all patients with single-segment disease an...

Journal: :JACC. Cardiovascular interventions 2015
Morton J Kern Arnold H Seto

F ractional flow reserve (FFR) works. After 20 years and 3 landmark clinical trials, FFR is arguably the best standard for determining the significance of coronary artery disease. By revealing a specific coronary stenosis’s ischemic potential, FFR often changes clinical decisions on the need for or method of revascularization, leading to demonstrably better clinical outcomes and costeffectivene...

Journal: :Circulation 2000
B De Bruyne N H Pijls G R Heyndrickx D Hodeige R Kirkeeide K L Gould

Background-Fractional flow reserve (FFR) is an index of stenosis severity validated for isolated stenoses. This study develops the theoretical basis and experimentally validates equations for predicting FFR of sequential stenoses separately. Methods and Results-For 2 stenoses in series, equations were derived to predict FFR (FFR(pred)) of each stenosis separately (ie, as if the other one were r...

2015
Dmitriy S. Sulimov Mohamed Abdel-Wahab Gert Richardt

In patients presenting with ST-segment elevation myocardial infarction (STEMI) and multi-vessel disease (MVD), the optimal therapy for non-culprit lesions is still a matter of debate. While guidelines discourage a concomitant treatment of infarct- and non-infarct-related arteries, recent studies document advantages of a complete (preventive) revascularization during primary percutaneous coronar...

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