نتایج جستجو برای: fractalkine
تعداد نتایج: 925 فیلتر نتایج به سال:
purification quality of CLP is important, especially for analyses of T-cell development. The original phenotypic CLP has recently been refined by addition of positivity for Flk25 and now a smaller population of cells including CD27 are shown to contain the T-cell potential. A specific criticism of the CLP as the thymus-seeding cell has been the lack of evidence that CLP can be detected in thymu...
The sensory organs of the inner ear possess resident populations of macrophages, but the function of those cells is poorly understood. In many tissues, macrophages participate in the removal of cellular debris after injury and can also promote tissue repair. The present study examined injury-evoked macrophage activity in the mouse utricle. Experiments used transgenic mice in which the gene for ...
Purpose To determine if cytokine tear levels before hematopoietic stem cell transplantation (HSCT) can help anticipate the occurrence of ocular chronic graft-versus-host disease (cGVHD). Methods In this pilot study, 25 patients undergoing HSCT were followed prospectively for ≤43 months. After ocular examinations, tears were collected before HSCT. Levels of 19 cytokines (epidermal growth facto...
BACKGROUND Parkinson disease (PD) is a progressive neurodegenerative disorder characterized by loss of dopamine neurons in the substantia nigra pars compacta (SNpc) and widespread aggregates of the protein alpha-synuclein (α-syn). Increasing evidence points to inflammation as a chief mediator; however, the role of α-syn in triggering and sustaining inflammation remains unclear. In models of Alz...
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