A case of gangrene of the hand following inadvertent intra-arterial injection of a pyrazole derivative (Tomanol) is presented. Gangrene of the hand and superficial sloughing of the distal arm necessitated a forearm amputation. Because of the serious sequelae, precautions must be taken to avoid inadvertent intra-arterial injections and due consideration must be given to the anatomical variation ...

While the use of x-rays to treat patients with gas gangrene ended in the early 1940's with the advent of antibiotics, x-ray had been widely accepted as a useful and highly effective treatment for this condition. The present paper re-assesses the historical foundations of this belief, the quality of the data, use of confirmatory animal models, and underlying mechanisms that might account for the...

Bacterial endocarditis is a complex disease associated with high morbidity and mortality with complications that include acute heart failure and arterial embolism. Venous thrombosis of the lower limbs is not uncommon following all forms of surgery, but infrequent following cardiac surgery, and rarely progresses to venous gangrene. We report a case of bilateral lower-limb venous gangrene, in a 4...

One hundred and seven profundaplasties have been performed for rest pain or gangrene due to advanced arterial degeneration below the inguinal ligament. Local anaesthesia was used for 78 operations. There were 19 early failures (2 deaths and 17 amputations) and 16 later amputations. During 4-5 years of follow-up, 25 other patients have died. The results for diabetic gangrene were worse than for ...

Penile gangrene is a rare but unfortunate complication of surgical intervention and priapism shunts. The literature regarding penile gangrene following surgical correction of priapism is sparse, the majority of which dates back to thirty to forty years. Here, we present the case of a 60-year-old man who presented with priapism that required operative management with a modified Al-Ghorab shunt a...

A series of 32 treated cases of Fournier's gangrene is analysed. All patients were male, their age ranged from 19 to 89 years. In 16 cases (50%) the aetiology of gangrene was urethral (37.5%), anorectal (12.5%) and in the 16 remaining cases (50%) there was no identifiable cause. Mortality was high (28%) despite broad spectrum antibiotics and aggressive surgical debridement. This mortality was e...

Fournier's gangrene is an uncommon pathological condition that affects the perineoscrotal region. Its course is fulminant and it carries a high mortality. We present 6 cases that had been treated over a period of 24 months. The mortality rate was 33.3%. The mean patient age was 53 years. The clinical and therapeutic aspects are discussed. The need to perform wide repeated debridement and the us...

A 51-year-old male with hepatitis C and a history of intravenous (IV) drug use presented to the emergency department, reporting one day of worsening scrotal pain and swelling. He denied diabetes, trauma, or infection with HIV. His genitourinary examination revealed a draining lesion in his left inguinal region with surrounding induration and cellulitis extending onto his perineum. His scrotum w...