Background: We have shown that thyroid hormones (THs) are cardioprotective and can be potentially used as safe therapeutic agents for diabetic cardiomyopathy and permanent infarction. However, no reliable, clinically translatable protocol exists for TH treatment of myocardial ischemia-reperfusion (IR) injury. We hypothesized that modified low-dose triiodo-L-thyronine (T3) therapy would confer s...

Atropa belladonna L. is the commercial plant to produce tropane alkaloids including hyoscyamine and scopolamine, which are widely used as anticholinergic agents. In the present study, the genes encoding the key enzymes including putrescine N-methyltransferase (PMT) and hyoscyamine 6β-hydroxylase (H6H) were simultaneously overexpressed in transgenic hairy root cultures of A. belladonna. All of t...

Serum free thyroxine (FT4), total T4 (T4) and total T3 (T3) were determined by radioimmunoassay in 1,114 adults during a periodic health evaluation to detect unsuspected thyroid dysfunction. As a result, 3 patients with hyperthyroidism, 4 with hypothyroidism, 3 taking thyroid medication, 4 with chronic thyroiditis, 1 with simple goiter and 3 women under estrogen administration were found. Free ...

Plasma thyroxine (T4), triiodothyronine (T3) and iodide levels were measured from birth until 30 days of age in 17 Holstein x Friesian (HF), 7 Salers and 7 Charolais calves born at term. The response of plasma T4 and T3 levels to bovine thyrotropin (TSH) injection was also compared in two groups of 9 HF calves 3hrs and 21 days, respectively, after birth. In the HF calves, plasma T4 and T3 level...

Late in gestation, the developing air space epithelium switches from chloride and fluid secretion to sodium and fluid absorption. Absorption requires Na-K-ATPase acting in combination with apical sodium entry mechanisms. Hypothyroidism inhibits perinatal fluid resorption, and thyroid hormone [triiodothyronine (T3)] stimulates adult alveolar epithelial cell (AEC) Na-K-ATPase. This study explored...

common infections encountered in children. Most bacterial infections are caused by Streptococcus pyogenes (1). In addition, resurgence of severe forms of disease caused by S. pyogenes has been detected in various parts of the world (2, 3). Although all S. pyogenes strains remain exquisitely sensitive to penicillin, erythromycin has been the drug of choice for individuals who cannot take penicil...

Abstract The aim of this study was to investigate the effect Lactobacillus reuteri E81 (LRE) probiotic supplementation on heat stress responses in chukar partridges ( Alectoris chukar). birds were divided into two groups, one which exposed (HS). Within each group, four subgroups, including 64 birds, created for three treatment doses (200, 400 or 600 mg/kg) LRE and control. experiment started wi...