نتایج جستجو برای: founder effect
تعداد نتایج: 1647862 فیلتر نتایج به سال:
Founder mutations, particularly 35delG in the GJB2 gene, have to a large extent contributed to the high frequency of autosomal recessive nonsyndromic hearing loss (ARNSHL). Mutations in transmembrane channel-like gene 1 (TMC1) cause ARNSHL. The p.R34X mutation is the most frequent known mutation in the TMC1 gene. To study the origin of this mutation and determine whether it arose in a common an...
to estimate how levels of genetic diversity in non-native populations are different from those of their source populations. While it is typically assumed that a significant loss of diversity will be associated with species introductions, the actual effect may be more complex, depending on propagule pressure and patterns of diversity and population structure in the native range of a species. We ...
Founder analysis is a method for analysis of nonrecombining DNA sequence data, with the aim of identification and dating of migrations into new territory. The method picks out founder sequence types in potential source populations and dates lineage clusters deriving from them in the settlement zone of interest. Here, using mtDNA, we apply the approach to the colonization of Europe, to estimate ...
this study was carried out to investigate the direct and indirect responses to selection for four-week body weight (4 week body (wk bw)) and four-week breast weight (4 week breast weight (wk brw)) and to determine the genetic contribution of reminder founders to the last generation. a total number of 351 birds were equally allocated to three lines, including two selected lines (s1 and s2 for bw...
The lake minnow (Eupallasella percnurus) is critically endangered. In this paper we characterize the genetic properties of this fish over its range of occurrence in Poland and propose the use of this knowledge in its active protection. Twelve populations of lake minnow from across its range in Poland were investigated. 13 microsatellite loci were investigated to evaluate genetic variation and d...
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