The Wnt/β-catenin signalling pathway plays an important role in the proliferation of neural cells, and hence it is the main focus of several research aimed at understanding neurodegenerative pathologies. In this paper we consider a compact model of the basic mechanisms of the Wnt/β-catenin pathway and we analyse its dynamics by application of an expressive temporal logic formalism, namely the H...

PHYSICIANS MUST KEEP CURRENT with clinical information to practice evidence-based medicine (EBM). In doing so, most prefer to seek evidence-based summaries, which give the clinical bottom line, or evidence-based practice guidelines. Resources that maintain these information summaries, however, currently include a limited number of common conditions. Thus, to answer many of their clinical questi...

This analysis introduces a generalization of the basic statistical concepts of expectation values and variance for non-Euclidean metrics induced by L-norms. The non-Euclidean L means are defined by exploiting the fundamental property of minimizing the L deviations that compose the L variance. These L expectation values embody a generic formal scheme of means characterization. Having the p-norm ...

This analysis introduces a generalization of the basic statistical concepts of expectation values and variance for non-Euclidean metrics induced by L-norms. The non-Euclidean L means are defined by exploiting the fundamental property of minimizing the L deviations that compose the L variance. These L expectation values embody a generic formal scheme of means characterization. Having the p-norm ...

Building upon the statistical framework of causal inference, we consider classical approaches to statistical analysis of randomized experiments. The use of randomized experiments in scientific inquiry goes back at least to the 19th century, but formal statistical methods to analyze these experiments were developed in early 20th century by J. Neyman and R. Fisher. The methods they developed were...

introduction: due to increased costs of health sector, much effort has been done to compare the performance of hospitals and measure their efficiency in recent years. the purpose of this study was to evaluate the relative efficiency of public and private hospitals in qom during 2007 using data envelopment analysis (dea) approach. methods: this was an applied and analytic study. the study popula...

Intelligence analysis is a complicated task that requires a high degree of analytical judgement under conditions of considerable uncertainty. This judgement is used to fill in the gaps in knowledge and is the analyst’s principal means of managing uncertainty. Much of intelligence analysis includes judging the relevance and the value of evidence to determine the likelihood of competing hypothese...