This paper reports an overview on the chemistry of the indole alkaloid goniomitine focusing, mainly, on the methods of synthesis related to this natural product and analogs.

The endoscopic endonasal approach (EEA) has been popularized in adults and has been applied to an expanding range of surgical modules and indications in this population. However, its clinical application in pediatric neurosurgery has been impeded by the differences in anatomical features and the relatively low incidence of diseases to which it is applicable. In this review article, we mainly di...

Increasing diffusion of self-service technologies (SSTs) on the points of sale impacts on traditional retailing from several perspectives. For instance, SSTs have direct effect on front-line employees. Indeed, they may cause a potential reduction in personal contacts with clients, reduction of workers, modifying the job conditions and so on. To date, the effect of SSTs on the points of sale has...

Background: English for Specific Purposes (ESP) courses should empower students to satisfy their language needs. However, at many Iranian universities, these courses are mostly taught based on the Grammar Translation Method focusing on teaching grammatical rules and reading comprehension. The present study aims at proposing an innovative approach for teaching English to Medical students that ca...

The ESMO World Congress on Gastrointestinal Cancer took place in Barcelona from the 22nd until the 25th of June and hosted just over 3500 participants and faculty members from around the world, representing nearly 100 countries. The meeting mainly covered malignancies affecting the gastrointestinal tract, focusing on personalized therapy and the multidisciplinary approach. In addition, novel mo...

Hierarchical clustering algorithms can be agglomerative or divisive, depending on how partitions are formed. Such algorithms have advantages mainly related to the desired level of granularity the partition should have. The work described in this paper approaches two hierarchical algorithms, one agglomerative (and three of its variants) and the other divisive, focusing on their performance in un...

Boolean networks are discrete dynamical systems extensively used to model biological regulatory networks. The dynamical analysis of these networks suffers from the combinatorial explosion of the state space, which grows exponentially with the number n of components. To face this problem, a classical approach consists in deducing from the interaction graph of the network, which only contains n v...

This paper describes one university’s approach to improving the quality of teaching and learning at the institutional level, based on the premise of improving the design of curriculum rather than focusing on the skills of teachers as such. The paper describes the process by which university-wide principles of curriculum design were defined and agreed, as well as the parallel campaigns needed to...