Nutritional support in acute renal failure must take into account the patient's catabolism and the treatment of the renal failure. Hypermetabolic failure is common in these patients, requiring continuous renal replacement therapy or daily hemodialysis. In patients with normal catabolism (urea nitrogen below 10 g/day) and preserved diuresis, conservative treatment can be attempted. In these pati...

The management of patients with acute renal failure (ARF) is very complex and requires meticulous attention to fluid, acid-base and electrolyte balance as well as the removal of uraemic toxins. Peritoneal dialysis (PD) is an important option for treatment of selected patients with ARF, particularly those who are haemodynamically compromised or have coagulation abnormalities. Due to continuous t...

INTRODUCTION Pharmacological therapy is a strategy for the prevention of complications associated with ischemia and reperfusion injury that occurs after volume replacement in the treatment of hemorrhagic shock. OBJECTIVE The aim of this study was to evaluate the effect of N-acetylcysteine associated with fluid resuscitation in cardiac injury in a rat hemorrhagic shock model. METHODS Mice Wi...

Hormone-replacement therapy (HRT) has been available for many years, but the important question of its place in development and progression of breast cancer remains controversial; provision of reliable risk estimates has been hampered by a lack of controlled data. Observational evidence suggests that the risk of breast cancer may be increased only if HRT is used long term (ie, for longer than 1...

A 65-year-old man was a diagnosed with meningitis and bacteremia, as Streptococcus pneumoniae was isolated from spinal fluid and blood cultures. After three weeks of antibiotic therapy, computed tomography revealed a ruptured aneurysm of the descending thoracic aorta. The aneurysm had appeared during the first episode of meningitis but had remained silent for two years. The patient underwent in...

The most common indication for continuous renal replacement therapy (CRRT) in critically ill patients is acute kidney injury with hemodynamic instability. Typically, the patient has metabolic disturbances and potential or actual fluid overload that require intervention. Certain critical care diagnoses and/or conditions or therapies present unique CRRT management approaches. Case vignettes are u...

brucella endocarditis is an uncommon but not rare manifestation of brucellosis in our country. we report six adult patients aged 20 to 45 years. two of our patients were female, and this is the first time that brucella endocarditis was reported in adult females. in five cases, aortic valve replacement was performed in addition to combined antibiotic therapy. one of them died due to immediate co...

Brucella endocarditis is an uncommon but not rare manifestation of brucellosis in our country. We report six adult patients aged 20 to 45 years. Two of our patients were female, and this is the first time that Brucella endocarditis was reported in adult females. In five cases, aortic valve replacement was performed in addition to combined antibiotic therapy. One of them died due to immedia...

In view of the benefits of hormone replacement therapy (HRT) and the experience that only 10% of women maintain therapy, it is vital that all doctors are familiar with the pros and cons of HRT, so that women may be correctly advised. Here we discuss new issues and developments in HRT and current views on indications, complications and regimens of treatment.

BACKGROUND Respiratory and renal insufficiencies are common dysfunctions during post-liver transplantation period that increase post-operative mortality and morbidity rates. Intra-operative fluid therapy is an important factor associated with pulmonary and renal insufficiency. OBJECTIVE To evaluate the relation between intra-operative fluid therapy and early renal and respiratory insufficienc...