Abstract. The purpose of this research was to develop and evaluate effervescent gastric floating tablets of propranolol HCl. The oral delivery of antihypertensive propranolol HCl was facilitated by preparing an effervescent floating dosage form which could increase its absorption in the stomach by increasing the drug's gastric residence time. In the present work, effervescent floating tablets w...

Simple floating point operations like addition or multiplication on normalized floating point values can nowadays be computed by current AMD and Intel processors in three to five cycles. This is different for denormalized numbers, which appear when an underflow occurs and the value can no longer be represented as a normalized floating-point value. Here the costs are about two magnitudes larger....

Local binary pattern (LBP) captures the local information of a texture effectively and thus plays a dominant role in many image processing applications. A LBP with (8, 1) or (8, 2) derives 2= 256 different patterns, to reduce this dimensionality uniform local binary patterns (ULBP) are derived and it has been proved that they capture fundamental properties of texture. The major disadvantage of ...

BACKGROUND Floating knee injuries are usually associated with other significant injuries. Do these injuries have implications on the management of the floating knee and the final outcome of patients? Our study aims to assess the implications of associated injuries in the management and final outcome of floating knee. METHODS 29 patients with floating knees were assessed in our institution. A ...

We present a new, open-source formalization of fixed and floating-point numbers for arbitrary radix and precision that is now part of the HOL Light distribution [10]. We prove correctness and error bounds for the four different rounding modes, and formalize a subset of the IEEE 754 [1] standard by gluing together a set of fixed-point and floating-point numbers to represent the subnormals and no...

The reform to convert non-floating shares to floating in China provides a setting in which shares are subject to different liquidity constraint. We show that the severity of this constraint is inversely related to the extent to which earnings information is reflected in the share prices. Specifically, before the reform, the transfer prices of non-floating shares reflect much less earnings infor...

Floating arm injury represents a common yet complicated injury of the childhood severely associated with limb deformation and even morbidity, if not precisely addressed and credibly operated. Here, we report a rare floating upper limb case of a 9-year-old boy with multiple injuries of ipsilateral proximal humeral, supracondylar and distal radial limb. This is the first report to document such a...

In this study, we have investigated variations in the potential of floating and submerged leaves of longleaf pondweed (Potamogeton nodosus) to withstand silver ion (Ag+)-toxicity. Both floating and submerged leaves changed clear colorless AgNO3 solutions to colloidal brown in the presence of light. Transmission electron microscopy revealed the presence of distinct crystalline Ag-nanoparticles (...

Objective: The main purpose of this study is to prepare a floating micro articulated drug delivery system of ciprofloxacin by using non-aqueous solvent evaporation technique to increase the bioavailability and therapeutic effectiveness of the drug by prolonging its gastric residence time. Methods: Floating microparticles were prepared by using different low-density polymers such as ethyl cellul...

Purpose. Effective Helicobacter pylori eradication requires delivery of the antibiotic locally in the stomach. High dose of amoxicillin (750 to 1000 mg) is difficult to incorporate in floating tablets but can easily be given in liquid dosage form. Keeping the above facts in mind, we made an attempt to develop a new floating in situ gelling system of amoxicillin with increased residence time usi...