نتایج جستجو برای: flat erg

تعداد نتایج: 65508  

ابوالفضل فراهانی, الهام محمدی اقدم یعقوب بدری آذرین

تحقیق حاضر با هدف تعیین ارتباط بین عوامل انگیزشی و تحلیل رفتگی شغلی دبیران تربیت بدنی شهر تبریز بر اساس مدل انگیزشی ERG صورت گرفته است. پژوهش حاضر توصیفی- همبستگی می باشد. از بین 500 نفر از دبیران تربیت بدنی مقطع راهنمایی و متوسطه تبریز تعداد 226 نفر با استفاده از جدول نمونه گیری مورگان در سال 1390 انتخاب گردید. از پرسشنامه نیازهای ERG و سیاهه فرسایش شغلی مسلوچ (MBI) برای گرد آوری داده های تحقی...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Dragos Niculescu Wiebke Hirdes Sönke Hornig Olaf Pongs Jürgen R Schwarz

We investigated the subthreshold properties of an erg (ether-à-go-go-related gene) K(+) current in Purkinje cells of neonatal mice. Action potentials recorded from Purkinje cells in cerebellar slices exhibited a decreased threshold potential and increased frequency of spontaneous and repetitive activity following application of the specific erg channel blocker E-4031. Accommodation was absent b...

Journal: :medical journal of islamic republic of iran 0
ba sbahriari from the dept. of ophthalmology, zahedan university of medical sciences, zahedan, ir.iran. am salari

in order to identify the effects of vitamin a and aspirin on reducing uv lightinduced retinopathy, erg waves were compared before and after uv light exposure in rabbits. 30 rabbits were divided into 3 groups: the first group received vitamin a, 50,000 units i.m., single dose, the second group received aspirin, 50 mg/ kg/day po and the third group did not receive any medication. all three groups...

2012
Xin Gao Liao-Yuan Li Fang-Jian Zhou Ke-Ji Xie Chun-Kui Shao Zu-Lan Su Qi-Peng Sun Ming-Kun Chen Jun Pang Xiang-Fu Zhou Jian-Guang Qiu Xing-Qiao Wen Ming Yang Xian-Zhong Bai Hao Zhang Li Ling Zhong Chen

Purpose: We aimed to analyze whether ERG rearrangement in biopsies could be used to assess subsequent cancer diagnosis in high-grade prostatic intraepithelial neoplasia (HGPIN) and the risk of lymph node metastasis in early prostate cancer. Experimental Design: Samples from 523 patients (361with early prostate cancer and 162withHGPIN) were collected prospectively. On the basis of the cutoff val...

Journal: :Molecular cancer therapeutics 2015
Payel Chatterjee Gaurav S Choudhary Turkeyah Alswillah Xiahui Xiong Warren D Heston Cristina Magi-Galluzzi Junran Zhang Eric A Klein Alexandru Almasan

Exposure to genotoxic agents, such as ionizing radiation (IR), produces DNA damage, leading to DNA double-strand breaks (DSB); IR toxicity is augmented when the DNA repair is impaired. We reported that radiosensitization by a PARP inhibitor (PARPi) was highly prominent in prostate cancer cells expressing the TMPRSS2-ERG gene fusion protein. Here, we show that TMPRSS2-ERG blocks nonhomologous en...

2017
A V Shah G M Birdsey C Peghaire M E Pitulescu N P Dufton Y Yang I Weinberg L Osuna Almagro L Payne J C Mason H Gerhardt R H Adams A M Randi

Notch and Angiopoietin-1 (Ang1)/Tie2 pathways are crucial for vascular maturation and stability. Here we identify the transcription factor ERG as a key regulator of endothelial Notch signalling. We show that ERG controls the balance between Notch ligands by driving Delta-like ligand 4 (Dll4) while repressing Jagged1 (Jag1) expression. In vivo, this regulation occurs selectively in the maturing ...

2016
Zineb Mounir Joshua M Korn Thomas Westerling Fallon Lin Christina A Kirby Markus Schirle Gregg McAllister Greg Hoffman Nadire Ramadan Anke Hartung Yan Feng David Randal Kipp Christopher Quinn Michelle Fodor Jason Baird Marie Schoumacher Ronald Meyer James Deeds Gilles Buchwalter Travis Stams Nicholas Keen William R Sellers Myles Brown Raymond A Pagliarini

The TMPRSS2:ERG gene fusion is common in androgen receptor (AR) positive prostate cancers, yet its function remains poorly understood. From a screen for functionally relevant ERG interactors, we identify the arginine methyltransferase PRMT5. ERG recruits PRMT5 to AR-target genes, where PRMT5 methylates AR on arginine 761. This attenuates AR recruitment and transcription of genes expressed in di...

Journal: :International ophthalmology clinics 1968
D Finkelstein P Gouras M Hoff

.raditional studies of the animal and human electroretinogram (ERG) indicate that the stimulus intensity necessary to evoke a minimal ERG from the dark adapted retina is well above the absolute threshold of vision; these studies also show that the ERG response at threshold consists of the b-wave only, and the a-wave appears at suprathreshold intensities. Recent work on the toad, rat, cat, monke...

2008
Amir Levinson

The rapid variability of the VHE emission reported for some TeV blazars implies Doppler factors well in excess of those inferred from superluminal motions and unification schemes. We propose that those extreme flares may result from radiative deceleration of blobs on scales where local dissipation occurs. The minimum jet power estimated from the resolved synchrotron emission on VLBI scales appe...

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