Mitochondria are remarkably dynamic organelles undergoing frequent fusion and fission events. Impairment thereof is linked to numerous neurodegenerative disorders and dysregulation of apoptosis. The principal players mediating mitochondrial fission are considered to be well known and largely conserved between yeast and mammals. However, how the essential fission factor Drp1 is recruited to mito...

................................................................................................... 1 2 SPALLATION NEUTRON SOURCE DESIGN ........................................... 3 3 SUBCRITICAL FISSION BLANKET DESIGN ........................................... 4 3.1 FISSION BLANKET NEUTRON MULTIPLICATION ................................................................ 4 3.2 FISSION BLANKET E...

The prompt neutron and γ emission from primary fission fragments are calculated for thermal neutron induced fission of 235U and 239Pu and for spontaneous fission of 252Cf using a Monte Carlo Hauser-Feshbach approach for the evaporation of the excited fission fragments. Remaining free model parameters, such as excitation energy sharing and initial spin distribution, are determined by comparison ...

We report on the first detailed atomic-scale studies of micelle fission in micellar systems consisting of anionic sodium dodecyl sulfate with explicit solvent. We demonstrate a new micelle fission pathway for ionic surfactants and show how micelle fission can be induced by varying the ionic concentration. We argue that this fission pathway proceeds through an initial Rayleigh instability driven...

In order to quantitatively understand the fission role in the r process, two important pieces of information are needed: The fission probabilities and massand charge-distributions of the fission fragments. Unfortunately, experimental information is available only for nuclei in a limited region of the nuclide chart, and for heavy r-process nuclei one has to rely on theoretical predictions. This ...

The naphthoquinones lapachol and dichloroallyl lawsone readily undergo oxidative ring fission when incubated with several fungi and streptomycetes. Penicillium notatum was employed to produce the ring fission product of dichloroallyl lawsone which was isolated and characterized by spectral analyses and chemical synthesis. The mechanism of oxidative ring fission of lapachol was studied by growin...

Measurements are presented of the photofission cross section and the mean number fi of neutrons per fission for 232Th made using bremsstrahlung from the Harwell electron linear accelerator HELIOS and a high efficiency neutron detector to record neutron multiplicity distributions. The cross section is interpreted in terms of a fission barrier with shallow wells in two separate outer barriers. In...

Using triple-coincidence events of prompt fission gamma rays from 1995 Gammasphere data on spontaneous fission of Cf, we made a careful analysis of the yield matrix of coincident pairs of barium (Z556) and molybdenum (Z542) fission fragments. Branching from gamma bands (K52) and octupole bands (K50) are presented for even-even partners, where observable. From this reanalysis the previously prop...

Eukaryotic gene fusion and fission events are mechanistically more complicated than in prokaryotes, and their quantitative contributions to genome evolution are still poorly understood. We have identified all differentially composite or split genes in 2 fully sequenced plant genomes, Oryza sativa and Arabidopsis thaliana. Out of 10,172 orthologous gene pairs, 60 (0.6% of the total) revealed a v...

Androgen and androgen receptors (AR) play critical roles in the proliferation of prostate cancer through transcriptional regulation of target genes. Here, we found that androgens upregulated the expression of dynamin-related protein 1 (Drp1), which is involved in the induction of mitochondrial fission, a common event in mitosis and apoptosis. Clinical tissue samples and various prostate cancer ...