PURPOSE Comparison of the demographic, ocular, systemic and microbiological characteristics of eyes with bleb related infection (BRI) and bleb related endophthalmitis (BRE). METHODS Retrospective chart review of patients with BRI from January 1996-July 2013. Identification done via the center's longstanding endophthalmitis audit, BRI audit and laboratory database identifying all conjunctival ...

OBJECTIVE To analyse blebs of phacotrabeculectomies performed with Ologen collagen implants (ProTop & MediKing, Taipei, Taiwan) and to compare these with blebs of mitomycin C (MMC)–augmented phacotrabeculectomies. METHODS 33 participants underwent phacotrabeculectomy with Ologen implants, and 33 controls underwent phacotrabeculectomy with MMC. Blebs were analysed for height and area using ant...

A prospective trial of topical antiprostaglandins versus placebo in the treatment of postoperative fistulising surgery followed up for 12 months is described. It is concluded that antiprostaglandins have little place in the management of these cases. A photographic record of evolution of the fistulising bleb is described, together with a scoring system devised for the evolution of the successfu...

Dear Editor, In trabeculectomy, maintaining bleb integrity is essential for preventing hypotony, infection, and exposure of the sclera. An amniotic membrane (AM) is often used to manage bleb integrity-related problems such as intraoperative buttonholes [1] and late postoperative bleb leakage [2-4]. Herein we present a case in which a large conjunctival bleb defect (6 × 3 mm) occurred during tra...

A cellular bleb grows when a portion of the cell membrane detaches from the underlying cortex under the influence of a cytoplasmic pressure. We develop a quantitative model for the growth and dynamics of these objects in a simple two-dimensional setting. In particular, we first find the minimum cytoplasmic pressure and minimum unsupported membrane length for a stationary bleb to nucleate and gr...

Purpose To examine the preoperative conjunctival dendritic cell density (DCD), goblet cell density (GCD), and stromal meshwork reflectivity (SMR) in glaucomatous patients undergoing filtration surgery, using in vivo confocal microscopy (IVCM). Methods Sixty-six patients were enrolled. At baseline, IVCM was performed at the site planned for surgery, and was repeated after 12 months at bleb sit...

BACKGROUND/AIMS Although adjunctive use of antiproliferative agents improves the success rate of glaucoma filtration surgery it profoundly alters the morphology of the filtering bleb. In view of these structural changes, which have been suggested to predispose to bleb infection, the relative importance of potential risk factors in the development of post-trabeculectomy endophthalmitis was inves...

OBJECTIVE Comparison of fornix- and limbus-based conjunctival flaps with respect to cystic bleb-related complications of trabeculectomy with high-dose mitomycin C (MMC) in pediatric and young adult glaucoma. DESIGN Retrospective nonrandomized comparative interventional case series. PARTICIPANTS Thirty-seven patients. METHODS Identification of patients aged <30 years from operating theater...

PURPOSE To evaluate the influence that vitreous incarceration may exert on the presence of postoperative conjunctival blebs over sclerotomies after transconjunctival sutureless vitrectomy (TSV). Blebs are formed by incisional leakage due to incompetent closure. METHODS Experimental study in which 23-gauge TSV was performed in 146 cadaveric pig eyes. Once the vitrectomy was finished, triamcino...

Trabeculectomy remains the standard surgery for intraocular pressure control for glaucoma. It involves a full thickness penetration of sclera, to allow aqueous seepage to subconjunctival space under a scleral flap. However, it carries the risk of serious bleb related complications like overfiltration, hypotony and consequent persistent choroidal detachment, shallow anterior chamber, cataract, p...