BACKGROUND Fibrous dysplasia is a slowly progressive benign fibro-osseous disorder that involves one or multiple bones with a unilateral distribution in most cases. It is a lesion of unknown etiology, uncertain pathogenesis, and diverse histopathology. Temporal bone involvement is the least frequently reported type, especially in children. We reviewed available articles regarding fibrous dyspla...

BACKGROUND Research into the optimal treatment of fibrous dysplasia has been limited by the lack of an established classification system for the disease. The purposes of this study were to develop a radiographic classification for fibrous dysplasia of the proximal femur and to test this classification's intra- and interobserver reliability as well as the effectiveness of our treatments. METHO...

Fibrous dysplasia is a benign intramedullary lesion characterized by an excessive proliferation of cellular fibrous tissue intermixed with irregular trabeculae. It involves any of the bones presenting as monostotic, polyostotic, or panostotic lesion. It is caused by mutation in the GNAS1 gene (20q13.2, encoding a G-protein) resulting in inhibition of intrinsic GTPase activity of Gs alpha protei...

Received 7/9/2003; revised 7/23/2003; accepted 8/10/2003. For correspondence or reprints contact: Yeh-You Shen, M.D., Department of Nuclear Medicine, Shin Kong Wu Ho-Su Memorial Hospital. 95 Wen-Chang Road, Shih Lin District, Taipei 111, Taiwan. Tel: (886)2-28332211 ext. 2280, Fax: (886)2-28389489, E-mail: [email protected] A 57-year-old female underwent whole-body F-fluorodeoxyglucose posi...

Fibrous dysplasia (FD) is a progressive systemic bone tumour of young and it can be seen on cranial bones. FD is divided into three types according to radiological features. The second most common subtype is polyostotic subtype. With this article, we aimed to review and present clinical features, radiological examination, differential diagnosis and treatment management of a case of solitary mon...

An unusual pervasive and persistent asymmetry in background rhythm was found on surface electroencephalography (EEG) recordings in a 22 year old with new onset of generalized seizure activity. Radiographic correlation with computed tomography, positron emission tomography and bone scan imaging uncovered that the higher amplitude left frontal-parietal background activity was related to a circums...

Fibrous dysplasia (FD) is a relatively uncommon disorder that affects primarily the cranial region; its occurrence in the cranial base in combination with hindbrain herniation and aneurysmal bone cyst (ABC) constitutes an extremely rare condition. We report a case of polyostotic fibrous dysplasia with progressive occipital, temporal, and clival involvement. Clinical findings and differential di...

Fibrous dysplasia (FD) is described as a growth disorder characterized by the progressive replacement of normal bone elements fibrous-osseus tissue. Bones affected FD presented with weakening and prone to pathological fracture. We reported case in an 8-years-old boy, who came hospital pain upper right thigh after falling bumps his head foot. An X-ray revealed deformity diasteal scalloping radio...