Background: 79% of the pregnant women suffer from sleep disorders. These disorders are the result of physiological, hormonal, physical changes, that occur in pregnancy due to different causes including fetal sex and maternal blood group. This study aimed to evaluate the relationship between fetal sex and maternal blood group with sleep disorders during pregnancy in the second and third trimeste...

The Potential Usefulness of Free Fetal DNA for Prenatal Gender Determination in Blood Plasma Pregnant Goat

UNLABELLED Cell-free fetal nucleic acids circulating in the blood of pregnant women afford the opportunity for early, noninvasive prenatal genetic testing. The predominance of admixed maternal genetic material in circulation demands innovative means for identification and analysis of cell-free fetal DNA and RNA. Techniques using polymerase chain reaction, mass spectrometry, and sequencing have ...

In previous years, identification of fetal cells in maternal blood circulation has caused a new revolution in non-invasive method of prenatal diagnosis. Low number of fetal cells in maternal blood and long-term survival after pregnancy limited the use of fetal cells in diagnostic and clinical applications. With the discovery of cell-free fetal DNA (cffDNA) in plasma of pregnant women, access to...

OBJECTIVE The detection of paternally inherited sequences in maternal plasma, such as the SRY gene for fetal sexing or RHD for fetal blood group genotyping, is becoming part of daily routine in diagnostic laboratories. Due to the low percentage of fetal DNA, it is crucial to ensure sample stability and the efficiency of DNA extraction. We evaluated blood stability at 4°C for at least 24 hours a...

The cytological evidence has revealed a visible mechanical basis for the production of males and females in equal numbers and irrespective of external conditions (Wilson, 1909).

The idea that the Dmrt1 gene provides a unifying sex-determining mechanism in non-mammalian vertebrates is left high and dry by recent observations in fish.