Mutations in daf-2 and age-1 cause a dramatic increase in longevity as well as developmental arrest at the dauer diapause stage in Caenorhabditis elegans. daf-2 and age-1 encode components of an insulin-like signaling pathway. Both daf-2 and age-1 act at a similar point in the genetic epistasis pathway for dauer arrest and longevity and regulate the activity of the daf-16 gene. Mutations in daf...

As access to anti-retroviral therapy (ART) increases in sub-Saharan Africa, fertility and contraception patterns are likely to change. Two hundred HIV-positive women at an ART roll-out site in Zimbabwe responded to a questionnaire on fertility desires and condom use. Ten women (5%) reported planning a pregnancy in the next year, comprising 0% of women not yet eligible for ART, 8.22% of women on...

OBJECTIVE To establish parameters associated with successful fimbriectomy reversal and to estimate monthly fecundability and cumulative pregnancy rates through life-table analysis. DESIGN Series report. SETTING University-based infertility clinic. PATIENT(S) Forty-one women undergoing surgery for tubal sterilization reversal. INTERVENTION(S) Surgical fimbriectomy reversal. MAIN OUTCOM...

This paper tests whether the fetal origins hypothesis (Barker 1992), which posits that disparities in the preand peri-natal environment can account for long-term disparities in life expectancy, is applicable to the case of variation in early circumstances due to wantedness. To identify the effects of wantedness on fertility rates and on life expectancy, we exploit over-time variation in the leg...

-the cowpea aphid, aphis craccivora koch, is an important pest of robinia pseudoacacia frisia. life table parameters of a. craccivora were determined under natural (16- 33ºc and 32-89% rh, respectively) and laboratory (25 ± 1ºc, rh of 70 ± 5% and a photoperiod of 16:8 h (l: d) conditions. the data were analyzed using the age-stage, two-sex life table theory. each experiment was replicated 45 ti...

background: northern regions of iran have been encountered to dominate malignancies of gastrointestinal (gi) tract. we came to examine the total excess mortality due to the gi cancer in mazandaran province. methods: socio-demographic and clinical data of 484 patients with gi cancer collected during the years 1990-1991were available from babol cancer registry. patients were followed up for 15 ye...

life table parameters of aphis pomi degeer (hemiptera: aphididae) were determined on two host plants: apple (malus pumila l.) and flowering quince (chaenomeles japonica lindl.). this study was carried out under laboratory conditions (25 ± 1 ºc and rh of 70 ± 5 % and a photoperiod of 16: 8 h (l: d). the survivorship from first instar nymphs to adult was very close in m. pumila and c. japonica. t...

BACKGROUND The life-course approach as a methodological framework for the empirical analysis of longitudinal individual-level data has fundamentally changed the agenda of demographic research. However, these methodological innovations have not been paralleled by a similarly successful theoretical integration in the life-course field. OBJECTIVE We aim to show that the life course is an indispens...

In this article data from the British Household Panel Study (BHPS) are used to analyse gender differences in fertility intentions, and the correspondence between fertility intentions and subsequent fertility behaviour. By exploiting couple-level data, we examine whether partners have conflicting preferences for future fertility. Focusing on women who remain childless in their thirties we look a...

It is estimated that in 2010, 1 in every 250 adults will be a childhood cancer survivor. Today, oncological surgery, radiotherapy and chemotherapy achieve relatively high rates of remission and long-term survival, yet are often detrimental to fertility. Quality of life is increasingly important to long-term survivors of cancer, and one of the major quality-of-life issues is the ability to produ...